Investigating the role of CLU PICALM and CR1 in Alzheimer's disease
In 2009, two large genome wide association studies (GWAS) found associations between common single nucleotide polymorphisms (SNPs) at three loci (CLU, PICALM and CR1) and Alzheimer’s disease (AD) risk. The causal variants underlying these associations and how these impact on AD susceptibility remain...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2014
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| Online Access: | http://eprints.nottingham.ac.uk/14273/ http://eprints.nottingham.ac.uk/14273/1/JennyLord_Thesis.pdf |