A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine

A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine

Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.

Bibliographic Details
Main Authors: Barthelme, Alexandre, Richards, David, Mellor, Ian R., Stockman, Robert A.
Format: Article
Language:English
Published: Royal Society of Chemistry 2013
Online Access:http://eprints.nottingham.ac.uk/35316/
http://eprints.nottingham.ac.uk/35316/
http://eprints.nottingham.ac.uk/35316/
http://eprints.nottingham.ac.uk/35316/1/ChemComm%202013.pdf
id nottingham-35316
recordtype eprints
spelling nottingham-353162017-10-13T16:57:19Z http://eprints.nottingham.ac.uk/35316/ A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine Barthelme, Alexandre Richards, David Mellor, Ian R. Stockman, Robert A. Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed. Royal Society of Chemistry 2013-11-18 Article PeerReviewed application/pdf en cc_by http://eprints.nottingham.ac.uk/35316/1/ChemComm%202013.pdf Barthelme, Alexandre and Richards, David and Mellor, Ian R. and Stockman, Robert A. (2013) A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine. Chemical Communications, 49 (89). pp. 10507-10509. ISSN 1364-548X http://pubs.rsc.org/en/Content/ArticleLanding/2013/CC/c3cc46800c#!divAbstract doi:10.1039/c3cc46800c doi:10.1039/c3cc46800c
repository_type Digital Repository
institution_category Local University
institution University of Nottingham Malaysia Campus
building Nottingham Research Data Repository
collection Online Access
language English
description Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.
format Article
author Barthelme, Alexandre
Richards, David
Mellor, Ian R.
Stockman, Robert A.
spellingShingle Barthelme, Alexandre
Richards, David
Mellor, Ian R.
Stockman, Robert A.
A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine
author_facet Barthelme, Alexandre
Richards, David
Mellor, Ian R.
Stockman, Robert A.
author_sort Barthelme, Alexandre
title A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine
title_short A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine
title_full A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine
title_fullStr A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine
title_full_unstemmed A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine
title_sort two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223b and (+/-)-xenovenine
publisher Royal Society of Chemistry
publishDate 2013
url http://eprints.nottingham.ac.uk/35316/
http://eprints.nottingham.ac.uk/35316/
http://eprints.nottingham.ac.uk/35316/
http://eprints.nottingham.ac.uk/35316/1/ChemComm%202013.pdf
first_indexed 2018-09-06T12:34:34Z
last_indexed 2018-09-06T12:34:34Z
_version_ 1610861536952188928

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