Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer’s disease

Screening exons 16 and 17 of the amyloid precursor protein gene in sporadic early-onset Alzheimer’s disease

Early-onset Alzheimer’s disease (EOAD) can be familial (FAD) or sporadic (sEOAD); both have a disease onset ≤ 65 years of age. 451 sEOAD samples were screened for known causative mutations in exon 16 and 17 of the Amyloid Precursor Protein gene (APP). Four samples were shown to be heterozygous for o...

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Main Authors: Barber, Imelda S., García-Cárdenas, Jennyfer M., Sakdapanichkul, Chidchanok, Deacon, Christopher, Zapata Erazo, Gabriela, Guerreiro, Rita, Bras, Jose, Hernandez, Dena, Singleton, Andrew, Guetta-Baranes, Tamar, Braae, Anne, Clement, Naomi, Patel, Tulsi, Brookes, Keeley, Medway, Christopher, Chappell, Sally, Mann, David M.
Format: Article
Language:English
Published: Elsevier 2016
Online Access:http://eprints.nottingham.ac.uk/31627/
http://eprints.nottingham.ac.uk/31627/
http://eprints.nottingham.ac.uk/31627/
http://eprints.nottingham.ac.uk/31627/1/1-s2.0-S0197458015006156-main.pdf

Internet

http://eprints.nottingham.ac.uk/31627/
http://eprints.nottingham.ac.uk/31627/
http://eprints.nottingham.ac.uk/31627/
http://eprints.nottingham.ac.uk/31627/1/1-s2.0-S0197458015006156-main.pdf

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