Mathematical modeling of genome replication

Eukaryotic DNA replication is initiated from multiple sites on the chromosome, but little is known about the global and local regulation of replication. We present a mathematical model for the spatial dynamics of DNA replication, which offers insight into the kinetics of replication in different typ...

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Bibliographic Details
Main Authors: Retkute, Renata, Nieduszynski, Conrad A., Moura, Alessandro de
Format: Article
Language:English
Published: American Physical Society 2012
Online Access:http://eprints.nottingham.ac.uk/2495/
http://eprints.nottingham.ac.uk/2495/
http://eprints.nottingham.ac.uk/2495/
http://eprints.nottingham.ac.uk/2495/1/Conrad_Nieduszynski--Mathematical_modeling.pdf