Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress

Hyperlipidemic microenvironment conditionates damage mechanisms in human chondrocytes by oxidative stress

Abstract Background Currently, two pathogenic pathways describe the role of obesity in osteoarthritis (OA); one through biomechanical stress, and the other by the contribution of systemic inflammation. The aim of this study was to evaluate the effect of free fatty acids (FFA) in human chondrocytes (...

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Main Authors: Daniel Medina-Luna, Mónica Guadalupe Santamaría-Olmedo, Yessica Zamudio-Cuevas, Karina Martínez-Flores, Javier Fernández-Torres, Gabriela Angélica Martínez-Nava, Denise Clavijo-Cornejo, Cristina Hernández-Díaz, Anell Olivos-Meza, Luis Enrique Gomez-Quiroz, María Concepción Gutiérrez-Ruiz, Carlos Pineda, Francisco Blanco, Anthony M. Reginato, Alberto López-Reyes
Format: Article
Language:English
Published: BioMed Central 2017-06-01
Series:Lipids in Health and Disease
Subjects:
Chondrocytes
Free fatty acids
Inflammation
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s12944-017-0510-x

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http://link.springer.com/article/10.1186/s12944-017-0510-x

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