Epigenetic regulation of MAGE family in human cancer progression-DNA methylation, histone modification, and non-coding RNAs

Epigenetic regulation of MAGE family in human cancer progression-DNA methylation, histone modification, and non-coding RNAs

Abstract The melanoma antigen gene (MAGE) proteins are a group of highly conserved family members that contain a common MAGE homology domain. Type I MAGEs are relevant cancer-testis antigens (CTAs), and originally considered as attractive targets for cancer immunotherapy due to their typically high...

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Bibliographic Details
Main Authors: Yishui Lian, Lingjiao Meng, Pingan Ding, Meixiang Sang
Format: Article
Language:English
Published: BioMed Central 2018-09-01
Series:Clinical Epigenetics
Subjects:
MAGE
Epigenetics
Transcription regulator
E3 RING ubiquitin ligases
Online Access:http://link.springer.com/article/10.1186/s13148-018-0550-8

Internet

http://link.springer.com/article/10.1186/s13148-018-0550-8

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