Background-deflection Brillouin microscopy reveals altered biomechanics of intracellular stress granules by ALS protein FUS

Giuseppe Antonacci et al. present a method for non-contact and label-free imaging using Brillouin microscopy to examine intracellular biomechanics at the sub-micron level. They use this approach in an analysis of stress granules containing ALS-related FUS protein mutants.

Bibliographic Details
Main Authors: Giuseppe Antonacci, Valeria de Turris, Alessandro Rosa, Giancarlo Ruocco
Format: Article
Language:English
Published: Nature Publishing Group 2018-09-01
Series:Communications Biology
Online Access:http://link.springer.com/article/10.1038/s42003-018-0148-x