Noncontact three-dimensional mapping of intracellular hydro-mechanical properties by Brillouin microscopy

Current measurements of the biomechanical properties of cells require physical contact with cells or lack sub-cellular resolution. Here, we developed a label-free optical microscopy technique based on Brillouin light scattering capable of measuring intracellular longitudinal modulus with optical res...

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Bibliographic Details
Main Authors: Scarcelli, Giuliano, Polacheck, William J., Nia, Hadi T., Patel, Kripa, Grodzinsky, Alan J., Kamm, Roger D., Yun, Seok Hyun
Format: Online
Language:English
Published: 2015
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666809/