Inhibition of destructive autoimmune arthritis in Fc?RIIa transgenic mice by small chemical entities

Inhibition of destructive autoimmune arthritis in Fc?RIIa transgenic mice by small chemical entities

The interaction of immune complexes with the human Fc receptor, Fc?RIIa, initiates the release of inflammatory mediators and is implicated in the pathogenesis of human autoimmune diseases, including rheumatoid arthritis and systemic lupus erythematosus, so this FcR is a potential target for therapy....

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Bibliographic Details
Main Authors: Pietersz, G., Mottram, P., Van De Velde, N., Sardjono, C., Esparon, S., Ramsland, Paul, Moloney, G., Baell, J., McCarthy, T., Matthews, B., Powell, M., Hogarth, P.
Format: Journal Article
Published: Nature Publishing Group 2009
Online Access:http://hdl.handle.net/20.500.11937/42104

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http://hdl.handle.net/20.500.11937/42104

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