Structural basis for Fc?RIIa recognition of human IgG and formation of inflammatory signaling complexes

The interaction of Abs with their specific FcRs is of primary importance in host immune effector systems involved in infection and inflammation, and are the target for immune evasion by pathogens. Fc?RIIa is a unique and the most widespread activating FcR in humans that through avid binding of immun...

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Bibliographic Details
Main Authors: Ramsland, Paul, Farrugia, W., Bradford, T., Sardjono, C., Esparon, S., Trist, H., Powell, M., Tan, P., Cendron, A., Wines, B., Scott, A., Hogarth, P.
Format: Journal Article
Published: 2011
Online Access:http://hdl.handle.net/20.500.11937/3683