The potential role of free chitosan in bone trauma and bone cancer management

Bone defects caused by fractures or cancer-mediated destruction are debilitating. Chitosan is commonly used in scaffold matrices for bone healing, but rarely as a free drug. We demonstrate that free chitosan promotes osteoblast proliferation and osteogenesis in mesenchymal stem cells, increases oste...

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Bibliographic Details
Main Authors: Tan, M., Shao, P., Friedhuber, A., van Moorst, M., Elahy, M., Indumathy, S., Dunstan, D., Wei, Y., Dass, Crispin
Format: Journal Article
Published: Elsevier Ltd 2014
Subjects:
Online Access:http://hdl.handle.net/20.500.11937/41787