Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy
Objectives: Bcl-2 is a protein that inhibits apoptosis, leading to cell survival. The Bcl-2 family has six different anti-apoptotic proteins, three pro-apoptotic proteins that are similar in structure, and other integrating proteins that function as promotors or inhibitors in the progression of apop...
Main Authors: | , , |
---|---|
Format: | Journal Article |
Published: |
John Wiley & Sons Ltd.
2012
|
Subjects: | |
Online Access: | http://hdl.handle.net/20.500.11937/12828 |