Local amplification of glucocorticoids in the aging brain and impaired spatial memory

by Yau, Joyce L. W., Seckl, Jonathan R.
Published 2012

Diurnal and stress‐induced intra‐hippocampal corticosterone rise attenuated in 11β‐HSD1‐deficient mice: a microdialysis study in young and aged mice

by Yau, Joyce L. W., Noble, June, Kenyon, Christopher J., Ludwig, Mike, Seckl, Jonathan R.
Published 2015

Intrahippocampal glucocorticoids generated by 11β-HSD1 affect memory in aged mice

by Yau, Joyce L.W., Wheelan, Nicola, Noble, June, Walker, Brian R., Webster, Scott P., Kenyon, Christopher J., Ludwig, Mike, Seckl, Jonathan R.
Published 2015

Cognitive and Disease-Modifying Effects of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition in Male Tg2576 Mice, a Model of Alzheimer's Disease

by Sooy, Karen, Noble, June, McBride, Andrew, Binnie, Margaret, Yau, Joyce L. W., Seckl, Jonathan R., Walker, Brian R., Webster, Scott P.
Published 2015

Short-term inhibition of 11β-hydroxysteroid dehydrogenase type 1 reversibly improves spatial memory but persistently impairs contextual fear memory in aged mice

by Wheelan, Nicola, Webster, Scott P., Kenyon, Christopher J., Caughey, Sarah, Walker, Brian R., Holmes, Megan C., Seckl, Jonathan R., Yau, Joyce L.W.
Published 2015