HER2 therapy. Small molecule HER-2 tyrosine kinase inhibitors

by Spector, Neil, Xia, Wenle, El-Hariry, Iman, Yarden, Yossi, Bacus, Sarah
Published 2007

Photo-Activated Psoralen Binds the ErbB2 Catalytic Kinase Domain, Blocking ErbB2 Signaling and Triggering Tumor Cell Apoptosis

by Xia, Wenle, Gooden, David, Liu, Leihua, Zhao, Sumin, Soderblom, Erik J., Toone, Eric J., Beyer, Wayne F., Walder, Harold, Spector, Neil L.
Published 2014

Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells

by Ren, Xiu-Rong, Wei, Junping, Lei, Gangjun, Wang, Jiangbo, Lu, Jiuyi, Xia, Wenle, Spector, Neil, Barak, Larry S, Clay, Timothy M, Osada, Takuya, Hamilton, Erika, Blackwell, Kimberly, Hobeika, Amy C, Morse, Michael A, Lyerly, H Kim, Chen, Wei
Published 2012

An heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models

by Xia, Wenle, Petricoin, Emanual F, Zhao, Sumin, Liu, Leihua, Osada, Takuya, Cheng, Qing, Wulfkuhle, Julia D, Gwin, William R, Yang, Xiaoyi, Gallagher, Rosa I, Bacus, Sarah, Lyerly, H Kim, Spector, Neil L
Published 2013

X-Ray Psoralen Activated Cancer Therapy (X-PACT)

by Oldham, Mark, Yoon, Paul, Fathi, Zak, Beyer, Wayne F., Adamson, Justus, Liu, Leihua, Alcorta, David, Xia, Wenle, Osada, Takuya, Liu, Congxiao, Yang, Xiao Y., Dodd, Rebecca D., Herndon, James E., Meng, Boyu, Kirsch, David G., Lyerly, H. Kim, Dewhirst, Mark W., Fecci, Peter, Walder, Harold, Spector, Neil L.
Published 2016