IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias

by Gusscott, Samuel, Jenkins, Catherine E., Lam, Sonya H., Giambra, Vincenzo, Pollak, Michael, Weng, Andrew P.
Published 2016

High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling

by Medyouf, Hind, Gusscott, Samuel, Wang, Hongfang, Tseng, Jen-Chieh, Wai, Carol, Nemirovsky, Oksana, Trumpp, Andreas, Pflumio, Francoise, Carboni, Joan, Gottardis, Marco, Pollak, Michael, Kung, Andrew L., Aster, Jon C., Holzenberger, Martin, Weng, Andrew P.
Published 2011

PKCθ Regulates T-Cell Leukemia-Initiating Activity via Reactive Oxygen Species

by Giambra, Vincenzo, Jenkins, Christopher R., Wang, Hongfang, Lam, Sonya H., Shevchuk, Olena O., Nemirovsky, Oksana, Wai, Carol, Gusscott, Sam, Chiang, Mark Y., Aster, Jon C., Humphries, R. Keith, Eaves, Connie, Weng, Andrew P.
Published 2012

Molecular etiology of an indolent lymphoproliferative disorder determined by whole-genome sequencing

by Parker, Jeremy D.K., Shen, Yaoqing, Pleasance, Erin, Li, Yvonne, Schein, Jacqueline E., Zhao, Yongjun, Moore, Richard, Wegrzyn-Woltosz, Joanna, Savage, Kerry J., Weng, Andrew P., Gascoyne, Randy D., Jones, Steven, Marra, Marco, Laskin, Janessa, Karsan, Aly
Published 2016

Cell Fate Decisions in Malignant Hematopoiesis: Leukemia Phenotype Is Determined by Distinct Functional Domains of the MN1 Oncogene

by Lai, Courteney K., Moon, Yeonsook, Kuchenbauer, Florian, Starzcynowski, Daniel T., Argiropoulos, Bob, Yung, Eric, Beer, Philip, Schwarzer, Adrian, Sharma, Amit, Park, Gyeongsin, Leung, Malina, Lin, Grace, Vollett, Sarah, Fung, Stephen, Eaves, Connie J., Karsan, Aly, Weng, Andrew P., Humphries, R. Keith, Heuser, Michael
Published 2014

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

by Kwiatkowski, Nicholas, Zhang, Tinghu, Rahl, Peter B, Abraham, Brian J, Reddy, Jessica, Ficarro, Scott B, Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Christopher R, Hannett, Nancy M, McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, Thomas, Mitsiades, Constantine, Weng, Andrew P, Brown, Jennifer R, Benes, Cyril H., Marto, Jarrod A, Young, Richard A, Gray, Nathanael S.
Published 2014