Exome Sequencing of Cell-Free DNA from Metastatic Cancer Patients Identifies Clinically Actionable Mutations Distinct from Primary Disease

by Butler, Timothy M., Johnson-Camacho, Katherine, Peto, Myron, Wang, Nicholas J., Macey, Tara A., Korkola, James E., Koppie, Theresa M., Corless, Christopher L., Gray, Joe W., Spellman, Paul T.
Published 2015

Patient-specific factors influence somatic variation patterns in von Hippel–Lindau disease renal tumours

by Fei, Suzanne S., Mitchell, Asia D., Heskett, Michael B., Vocke, Cathy D., Ricketts, Christopher J., Peto, Myron, Wang, Nicholas J., Sönmez, Kemal, Linehan, W. Marston, Spellman, Paul T.
Published 2016

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

by Daemen, Anneleen, Wolf, Denise M., Korkola, James E., Griffith, Obi L., Frankum, Jessica R., Brough, Rachel, Jakkula, Lakshmi R., Wang, Nicholas J., Natrajan, Rachael, Reis-Filho, Jorge S., Lord, Christopher J., Ashworth, Alan, Spellman, Paul T., Gray, Joe W., van’t Veer, Laura J.
Published 2012

Cellular androgen content influences enzalutamide agonism of F877L mutant androgen receptor

by Coleman, Daniel J., Van Hook, Kathryn, King, Carly J., Schwartzman, Jacob, Lisac, Robert, Urrutia, Joshua, Sehrawat, Archana, Woodward, Josha, Wang, Nicholas J., Gulati, Roman, Thomas, George V., Beer, Tomasz M., Gleave, Martin, Korkola, James E., Gao, Lina, Heiser, Laura M., Alumkal, Joshi J.
Published 2016

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

by Shain, A. Hunter, Garrido, Maria, Botton, Thomas, Talevich, Eric, Yeh, Iwei, Sanborn, J. Zachary, Chung, Jongsuk, Wang, Nicholas J., Kakavand, Hojabr, Mann, Graham J., Thompson, John F., Wiesner, Thomas, Roy, Ritu, Olshen, Adam B., Gagnon, Alexander, Gray, Joe W., Huh, Nam, Hur, Joe S., Busam, Klaus J., Scolyer, Richard A., Cho, Raymond J., Murali, Rajmohan, Bastian, Boris C.
Published 2015

Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer

by Korkola, James E., Collisson, Eric A., Heiser, Laura, Oates, Chris, Bayani, Nora, Itani, Sleiman, Esch, Amanda, Thompson, Wallace, Griffith, Obi L., Wang, Nicholas J., Kuo, Wen-Lin, Cooper, Brian, Billig, Jessica, Ziyad, Safiyyah, Hung, Jenny L., Jakkula, Lakshmi, Feiler, Heidi, Lu, Yiling, Mills, Gordon B., Spellman, Paul T., Tomlin, Claire, Mukherjee, Sach, Gray, Joe W.
Published 2015

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

by Hu, Zhi, Mao, Jian-Hua, Curtis, Christina, Huang, Ge, Gu, Shenda, Heiser, Laura, Lenburg, Marc E., Korkola, James E., Bayani, Nora, Samarajiwa, Shamith, Seoane, Jose A., A. Dane, Mark, Esch, Amanda, Feiler, Heidi S., Wang, Nicholas J., Hardwicke, Mary Ann, Laquerre, Sylvie, Jackson, Jeff, W. Wood, Kenneth, Weber, Barbara, Spellman, Paul T., Aparicio, Samuel, Wooster, Richard, Caldas, Carlos, Gray, Joe W.
Published 2016

Timing chromosomal abnormalities using mutation data

by Durinck, Steffen, Ho, Christine, Wang, Nicholas J, Liao, Wilson, Jakkula, Lakshmi R, Collisson, Eric A, Pons, Jennifer, Chan, Sai-Wing, Lam, Ernest T, Chu, Catherine, Park, Kyunghee, Hong, Sung-woo, Hur, Joe S, Huh, Nam, Neuhaus, Isaac M, Yu, Siegrid S, Grekin, Roy C, Mauro, Theodora M, Cleaver, James E, Kwok, Pui-Yan, LeBoit, Philip E, Getz, Gad, Cibulskis, Kristian, Aster, Jon C, Huang, Haiyan, Purdom, Elizabeth, Li, Jian, Bolund, Lars, Arron, Sarah T, Gray, Joe W, Spellman, Paul T, Cho, Raymond J
Published 2011

Modeling precision treatment of breast cancer

by Daemen, Anneleen, Griffith, Obi L, Heiser, Laura M, Wang, Nicholas J, Enache, Oana M, Sanborn, Zachary, Pepin, Francois, Durinck, Steffen, Korkola, James E, Griffith, Malachi, Hur, Joe S, Huh, Nam, Chung, Jongsuk, Cope, Leslie, Fackler, Mary Jo, Umbricht, Christopher, Sukumar, Saraswati, Seth, Pankaj, Sukhatme, Vikas P, Jakkula, Lakshmi R, Lu, Yiling, Mills, Gordon B, Cho, Raymond J, Collisson, Eric A, van’t Veer, Laura J, Spellman, Paul T, Gray, Joe W
Published 2013

Erratum to: Modeling precision treatment of breast cancer

by Daemen, Anneleen, Griffith, Obi L, Heiser, Laura M, Wang, Nicholas J, Enache, Oana M, Sanborn, Zachary, Pepin, Francois, Durinck, Steffen, Korkola, James E, Griffith, Malachi, Hur, Joe S, Huh, Nam, Chung, Jongsuk, Cope, Leslie, Fackler, Mary Jo, Umbricht, Christopher, Sukumar, Saraswati, Seth, Pankaj, Sukhatme, Vikas P, Jakkula, Lakshmi R, Lu, Yiling, Mills, Gordon B, Cho, Raymond J, Collisson, Eric A, van’t Veer, Laura J, Spellman, Paul T, Gray, Joe W
Published 2015