Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells

by Gloster, Tracey M., Zandberg, Wesley F., Heinonen, Julia E., Shen, David L., Deng, Lehua, Vocadlo, David J.
Published 2011

Structural snapshots of the reaction coordinate for O-GlcNAc transferase

by Lazarus, Michael B., Jiang, Jiaoyang, Gloster, Tracey M., Zandberg, Wesley F., Whitworth, Garrett E., Vocadlo, David J., Walker, Suzanne
Published 2012

Mechanism of Human Nucleocytoplasmic Hexosaminidase D

by Alteen, Matthew G., Oehler, Verena, Nemčovičová, Ivana, Wilson, Iain B. H., Vocadlo, David J., Gloster, Tracey M.
Published 2016

The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams

by Stubbs, Keith A, Bacik, John-Paul, Perley-Robertson, G Evan, Whitworth, Garrett E, Gloster, Tracey M, Vocadlo, David J, Mark, Brian L
Published 2013

Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds

by He, Xu, Pierce, Owen, Haselhorst, Thomas, von Itzstein, Mark, Kolarich, Daniel, Packer, Nicolle H, Gloster, Tracey M, Vocadlo, David J, Qian, Yi, Brooks, Doug, Kermode, Allison R
Published 2013

Differential Effects of an O-GlcNAcase Inhibitor on Tau Phosphorylation

by Yu, Yang, Zhang, Lan, Li, Xiaojing, Run, Xiaoqin, Liang, Zhihou, Li, Yi, Liu, Ying, Lee, Moon H., Grundke-Iqbal, Inge, Iqbal, Khalid, Vocadlo, David J., Liu, Fei, Gong, Cheng-Xin
Published 2012

Pharmacological inhibition of O-GlcNAcase (OGA) prevents cognitive decline and amyloid plaque formation in bigenic tau/APP mutant mice

by Yuzwa, Scott A, Shan, Xiaoyang, Jones, Bryan A, Zhao, Gang, Woodward, Melissa L, Li, Xiaojing, Zhu, Yanping, McEachern, Ernest J, Silverman, Michael A, Watson, Neil V, Gong, Cheng-Xin, Vocadlo, David J
Published 2014