The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to β-Lactams
The increasing incidence of inducible chromosomal AmpC β-lactamases within the clinic is a growing concern because these enzymes deactivate a broad range of even the most recently developed β-lactam antibiotics. As a result, new strategies are needed to block the action of this antibiotic resistance...
| Main Authors: | , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
WILEY-VCH Verlag
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3920638/ |