Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling

by Horn, Margaux A., Trafford, Andrew W.
Published 2016

Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P3 and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response

by Bennett, Hayley J., Davenport, John Bernard, Collins, Richard F., Trafford, Andrew W., Pinali, Christian, Kitmitto, Ashraf
Published 2013

Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes

by Briston, Sarah J., Dibb, Katharine M., Solaro, R. John, Eisner, David A., Trafford, Andrew W.
Published 2014

Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions

by Greensmith, David J., Galli, Gina L.J., Trafford, Andrew W., Eisner, David A.
Published 2014

Localised micro-mechanical stiffening in the ageing aorta

by Graham, Helen K., Akhtar, Riaz, Kridiotis, Constantinos, Derby, Brian, Kundu, Tribikram, Trafford, Andrew W., Sherratt, Michael J.
Published 2011

Phosphodiesterase type-5 inhibitor use in type 2 diabetes is associated with a reduction in all-cause mortality

by Anderson, Simon G, Hutchings, David C, Woodward, Mark, Rahimi, Kazem, Rutter, Martin K, Kirby, Mike, Hackett, Geoff, Trafford, Andrew W, Heald, Adrian H
Published 2016

Temporal Development of Autonomic Dysfunction in Heart Failure: Effects of Age in an Ovine Rapid-pacing Model

by Horn, Margaux A., Bode, Elizabeth F., Borland, Samantha J., Kirkwood, Graeme J., Briston, Sarah J., Richards, Mark A., Dibb, Katharine M., Trafford, Andrew W.
Published 2016

Perturbed atrial calcium handling in an ovine model of heart failure: Potential roles for reductions in the L-type calcium current

by Clarke, Jessica D., Caldwell, Jessica L., Horn, Margaux A., Bode, Elizabeth F., Richards, Mark A., Hall, Mark C.S., Graham, Helen K., Briston, Sarah J., Greensmith, David J., Eisner, David A., Dibb, Katharine M., Trafford, Andrew W.
Published 2015