A Missing PD-L1/PD-1 Coinhibition Regulates Diabetes Induction by Preproinsulin-Specific CD8 T-Cells in an Epitope-Specific Manner

by Schuster, Cornelia, Brosi, Helen, Stifter, Katja, Boehm, Bernhard O., Schirmbeck, Reinhold
Published 2013

An Inducible Transgenic Mouse Model for Immune Mediated Hepatitis Showing Clearance of Antigen Expressing Hepatocytes by CD8+ T Cells

by Cebula, Marcin, Ochel, Aaron, Hillebrand, Upneet, Pils, Marina C., Schirmbeck, Reinhold, Hauser, Hansjörg, Wirth, Dagmar
Published 2013

Effective intrahepatic CD8+ T-cell immune responses are induced by low but not high numbers of antigen-expressing hepatocytes

by Ochel, Aaron, Cebula, Marcin, Riehn, Mathias, Hillebrand, Upneet, Lipps, Christoph, Schirmbeck, Reinhold, Hauser, Hansjörg, Wirth, Dagmar
Published 2016

High-Resolution PET Imaging with Therapeutic Antibody-based PD-1/PD-L1 Checkpoint Tracers

by Hettich, Michael, Braun, Friederike, Bartholomä, Mark D., Schirmbeck, Reinhold, Niedermann, Gabriele
Published 2016

Exploring the induction of preproinsulin-specific Foxp3+ CD4+ Treg cells that inhibit CD8+ T cell-mediated autoimmune diabetes by DNA vaccination

by Stifter, Katja, Schuster, Cornelia, Schlosser, Michael, Boehm, Bernhard Otto, Schirmbeck, Reinhold
Published 2016

Hepatitis B virus genome replication triggers toll-like receptor 3-dependent interferon responses in the absence of hepatitis B surface antigen

by Real, Catherine Isabell, Lu, Mengji, Liu, Jia, Huang, Xuan, Trippler, Martin, Hossbach, Markus, Deckert, Jochen, Jahn-Hofmann, Kerstin, Ickenstein, Ludger Markus, John, Matthias Johannes, Gibbert, Kathrin, Dittmer, Ulf, Vornlocher, Hans-Peter, Schirmbeck, Reinhold, Gerken, Guido, Schlaak, Joerg Friedrich, Broering, Ruth
Published 2016