Large-scale integration of small molecule-induced genome-wide transcriptional responses, Kinome-wide binding affinities and cell-growth inhibition profiles reveal global trends cha...

by Vidović, Dušica, Koleti, Amar, Schürer, Stephan C.
Published 2014

High quality, small molecule-activity datasets for kinase research

by Sharma, Rajan, Schürer, Stephan C., Muskal, Steven M.
Published 2016

BioAssay Ontology (BAO): a semantic description of bioassays and high-throughput screening results

by Visser, Ubbo, Abeyruwan, Saminda, Vempati, Uma, Smith, Robin P, Lemmon, Vance, Schürer, Stephan C
Published 2011

Large-Scale Computational Screening Identifies First in Class Multitarget Inhibitor of EGFR Kinase and BRD4

by Allen, Bryce K., Mehta, Saurabh, Ember, Stewart W. J., Schonbrunn, Ernst, Ayad, Nagi, Schürer, Stephan C.
Published 2015

Fast and accurate semantic annotation of bioassays exploiting a hybrid of machine learning and user confirmation

by Clark, Alex M., Bunin, Barry A., Litterman, Nadia K., Schürer, Stephan C., Visser, Ubbo
Published 2014

Formalization, Annotation and Analysis of Diverse Drug and Probe Screening Assay Datasets Using the BioAssay Ontology (BAO)

by Vempati, Uma D., Przydzial, Magdalena J., Chung, Caty, Abeyruwan, Saminda, Mir, Ahsan, Sakurai, Kunie, Visser, Ubbo, Lemmon, Vance P., Schürer, Stephan C.
Published 2012

Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

by Wang, Likun, Perera, B. Gayani K., Hari, Sanjay B., Bhhatarai, Barun, Backes, Bradley J., Seeliger, Markus A., Schürer, Stephan C., Oakes, Scott A., Papa, Feroz R., Maly, Dustin J.
Published 2012

Suppression of TH17 Differentiation and Autoimmunity by a Synthetic ROR Ligand

by Solt, Laura A., Kumar, Naresh, Nuhant, Philippe, Wang, Yongjun, Lauer, Janelle L., Liu, Jin, Istrate, Monica A., Kamenecka, Theodore M., Roush, William R., Vidović, Dušica, Schürer, Stephan C., Xu, Jihong, Wagoner, Gail, Drew, Paul D., Griffin, Patrick R., Burris, Thomas P.
Published 2011

Anti-Diabetic Actions of a Non-Agonist PPARγ Ligand Blocking Cdk5-Mediated Phosphorylation

by Choi, Jang Hyun, Banks, Alexander S., Kamenecka, Theodore M., Busby, Scott A., Chalmers, Michael J., Kumar, Naresh, Kuruvilla, Dana S., Shin, Youseung, He, Yuanjun, Bruning, John B., Marciano, David P., Cameron, Michael D., Laznik, Dina, Jurczak, Michael J., Schürer, Stephan C., Vidović, Dušica, Shulman, Gerald I., Spiegelman, Bruce M., Griffin, Patrick R.
Published 2011

Evolving BioAssay Ontology (BAO): modularization, integration and applications

by Abeyruwan, Saminda, Vempati, Uma D, Küçük-McGinty, Hande, Visser, Ubbo, Koleti, Amar, Mir, Ahsan, Sakurai, Kunie, Chung, Caty, Bittker, Joshua A, Clemons, Paul A, Brudz, Steve, Siripala, Anosha, Morales, Arturo J, Romacker, Martin, Twomey, David, Bureeva, Svetlana, Lemmon, Vance, Schürer, Stephan C
Published 2014

CLO: The cell line ontology

by Sarntivijai, Sirarat, Lin, Yu, Xiang, Zuoshuang, Meehan, Terrence F, Diehl, Alexander D, Vempati, Uma D, Schürer, Stephan C, Pang, Chao, Malone, James, Parkinson, Helen, Liu, Yue, Takatsuki, Terue, Saijo, Kaoru, Masuya, Hiroshi, Nakamura, Yukio, Brush, Matthew H, Haendel, Melissa A, Zheng, Jie, Stoeckert, Christian J, Peters, Bjoern, Mungall, Christopher J, Carey, Thomas E, States, David J, Athey, Brian D, He, Yongqun
Published 2014