Stem vs non-stem cell origin of colorectal cancer

by Huels, D J, Sansom, O J
Published 2015

Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis

by Ahmad, I, Patel, R, Liu, Y, Singh, L B, Taketo, M M, Wu, X-R, Leung, H Y, Sansom, O J
Published 2011

Exploiting inflammation for therapeutic gain in pancreatic cancer

by Steele, C W, Jamieson, N B, Evans, T R J, McKay, C J, Sansom, O J, Morton, J P, Carter, C R
Published 2013

Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5<sup>+</sup> stem cells

by Flanagan, D., Phesse, T., Barker, N., Schwab, R., Amin, N., Malaterre, J., Stange, D., Nowell, C., Currie, S., Saw, J., Beuchert, E., Ramsay, R., Sansom, O., Ernst, M., Clevers, H., Vincan, Elizabeth
Published 2015

Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation

by Radulescu, S, Ridgway, R A, Cordero, J, Athineos, D, Salgueiro, P, Poulsom, R, Neumann, J, Jung, A, Patel, S, Woodgett, J, Barker, N, Pritchard, D M, Oien, K, Sansom, O J
Published 2013

NFκB signalling is upregulated in a subset of castrate-resistant prostate cancer patients and correlates with disease progression

by McCall, P, Bennett, L, Ahmad, I, MacKenzie, L M, Forbes, I W G, Leung, H Y, Sansom, O J, Orange, C, Seywright, M, Underwood, M A, Edwards, J
Published 2012

Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo

by Phesse, T J, Myant, K B, Cole, A M, Ridgway, R A, Pearson, H, Muncan, V, van den Brink, G R, Vousden, K H, Sears, R, Vassilev, L T, Clarke, A R, Sansom, O J
Published 2014

Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion

by Muller, P A J, Trinidad, A G, Timpson, P, Morton, J P, Zanivan, S, van den Berghe, P V E, Nixon, C, Karim, S A, Caswell, P T, Noll, J E, Coffill, C R, Lane, D P, Sansom, O J, Neilsen, P M, Norman, J C, Vousden, K H
Published 2013