Upcoming translational challenges for uveal melanoma

by Amirouchene-Angelozzi, Nabil, Schoumacher, Marie, Stern, Marc-Henri, Cassoux, Nathalie, Desjardins, Laurence, Piperno-Neumann, Sophie, Lantz, Olivier, Roman-Roman, Sergio
Published 2015

The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma

by Amirouchene-Angelozzi, Nabil, Frisch-Dit-Leitz, Estelle, Carita, Guillaume, Dahmani, Ahmed, Raymondie, Chloé, Liot, Géraldine, Gentien, David, Némati, Fariba, Decaudin, Didier, Roman-Roman, Sergio, Schoumacher, Marie
Published 2016

Cancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage

by Alsafadi, Samar, Houy, Alexandre, Battistella, Aude, Popova, Tatiana, Wassef, Michel, Henry, Emilie, Tirode, Franck, Constantinou, Angelos, Piperno-Neumann, Sophie, Roman-Roman, Sergio, Dutertre, Martin, Stern, Marc-Henri
Published 2016

Transcriptome Analysis of Wnt3a-Treated Triple-Negative Breast Cancer Cells

by Maubant, Sylvie, Tesson, Bruno, Maire, Virginie, Ye, Mengliang, Rigaill, Guillem, Gentien, David, Cruzalegui, Francisco, Tucker, Gordon C., Roman-Roman, Sergio, Dubois, Thierry
Published 2015

Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings

by Bieche, Ivan, Vacher, Sophie, Vallerand, David, Richon, Sophie, Hatem, Rana, De Plater, Ludmilla, Dahmani, Ahmed, Némati, Fariba, Angevin, Eric, Marangoni, Elisabetta, Roman-Roman, Sergio, Decaudin, Didier, Dangles-Marie, Virginie
Published 2014

Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma

by Carita, Guillaume, Frisch-Dit-Leitz, Estelle, Dahmani, Ahmed, Raymondie, Chloé, Cassoux, Nathalie, Piperno-Neumann, Sophie, Némati, Fariba, Laurent, Cécile, De Koning, Leanne, Halilovic, Ensar, Jeay, Sebastien, Wylie, Andrew, Emery, Caroline, Roman-Roman, Sergio, Schoumacher, Marie, Decaudin, Didier
Published 2016

Predictive Gene Signature of Response to the Anti-TweakR mAb PDL192 in Patient-Derived Breast Cancer Xenografts

by de Plater, Ludmilla, Vincent-Salomon, Anne, Berger, Frédérique, Nicolas, André, Vacher, Sophie, Gravier, Eléonore, Thuleau, Aurélie, Karboul, Narjesse, Richardson, Marion, Elbaz, Clément, Marangoni, Elisabetta, Bièche, Ivan, Paoletti, Xavier, Roman-Roman, Sergio, Culp, Patricia A., Asselain, Bernard, Diéras, Véronique, Decaudin, Didier
Published 2014

TTK/hMPS1 Is an Attractive Therapeutic Target for Triple-Negative Breast Cancer

by Maire, Virginie, Baldeyron, Céline, Richardson, Marion, Tesson, Bruno, Vincent-Salomon, Anne, Gravier, Eléonore, Marty-Prouvost, Bérengère, De Koning, Leanne, Rigaill, Guillem, Dumont, Aurélie, Gentien, David, Barillot, Emmanuel, Roman-Roman, Sergio, Depil, Stéphane, Cruzalegui, Francisco, Pierré, Alain, Tucker, Gordon C., Dubois, Thierry
Published 2013

Molecular profiling of patient-derived breast cancer xenografts

by Reyal, Fabien, Guyader, Charlotte, Decraene, Charles, Lucchesi, Carlo, Auger, Nathalie, Assayag, Franck, De Plater, Ludmilla, Gentien, David, Poupon, Marie-France, Cottu, Paul, De Cremoux, Patricia, Gestraud, Pierre, Vincent-Salomon, Anne, Fontaine, Jean-Jacques, Roman-Roman, Sergio, Delattre, Olivier, Decaudin, Didier, Marangoni, Elisabetta
Published 2012

Mutational analysis of anal cancers demonstrates frequent PIK3CA mutations associated with poor outcome after salvage abdominoperineal resection

by Cacheux, Wulfran, Rouleau, Etienne, Briaux, Adrien, Tsantoulis, Petros, Mariani, Pascale, Richard-Molard, Marion, Buecher, Bruno, Dangles-Marie, Virginie, Richon, Sophie, Lazartigues, Julien, Jeannot, Emmanuelle, Farkhondeh, Fereshteh, Sastre-Garau, Xavier, de La Rochefordière, Anne, Labib, Alain, Falcou, Marie-Christine, Stevens, Denise, Roth, Arnaud, Roman-Roman, Sergio, Mitry, Emmanuel, Bièche, Ivan, Lièvre, Astrid
Published 2016

Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

by Legrier, Marie-Emmanuelle, Bièche, Ivan, Gaston, Julie, Beurdeley, Arnaud, Yvonnet, Vanessa, Déas, Olivier, Thuleau, Aurélie, Château-Joubert, Sophie, Servely, Jean-Luc, Vacher, Sophie, Lassalle, Myriam, Depil, Stéphane, C Tucker, Gordon, Fontaine, Jean-Jacques, Poupon, Marie-France, Roman-Roman, Sergio, Judde, Jean-Gabriel, Decaudin, Didier, Cairo, Stefano, Marangoni, Elisabetta
Published 2016

Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization

by Vallerand, David, Massonnet, Gérald, Kébir, Fatima, Gentien, David, Maciorowski, Zofia, De la Grange, Pierre, Sigal-Zafrani, Brigitte, Richardson, Marion, Humbert, Sandrine, Thuleau, Aurélie, Assayag, Franck, de Plater, Ludmilla, Nicolas, André, Scholl, Suzy, Marangoni, Elisabetta, Weigand, Stefan, Roman-Roman, Sergio, Savina, Ariel, Decaudin, Didier
Published 2016