Combinations of targeted therapies in human cancers

by Decaudin, Didier, Le Tourneau, Christophe
Published 2016

Human breast cancer and lymph node metastases express Gb3 and can be targeted by STxB-vectorized chemotherapeutic compounds

by Stimmer, Lev, Dehay, Sabrina, Nemati, Fariba, Massonnet, Gerald, Richon, Sophie, Decaudin, Didier, Klijanienko, Jerzy, Johannes, Ludger
Published 2014

Impact of imatinib on the pharmacokinetics and in vivo efficacy of etoposide and/or ifosfamide

by Rezaï, Keyvan, Lokiec, François, Grandjean, Isabelle, Weill, Sophie, de Cremoux, Patricia, Bordier, Vincent, Ekue, Richard, Garcia, Mickael, Poupon, Marie-France, Decaudin, Didier
Published 2007

Specific Targeting of Caspase-9/PP2A Interaction as Potential New Anti-Cancer Therapy

by Arrouss, Issam, Nemati, Fariba, Roncal, Fernando, Wislez, Marie, Dorgham, Karim, Vallerand, David, Rabbe, Nathalie, Karboul, Narjesse, Carlotti, Françoise, Bravo, Jeronimo, Mazier, Dominique, Decaudin, Didier, Rebollo, Angelita
Published 2013

The mTOR inhibitor Everolimus synergizes with the PI3K inhibitor GDC0941 to enhance anti-tumor efficacy in uveal melanoma

by Amirouchene-Angelozzi, Nabil, Frisch-Dit-Leitz, Estelle, Carita, Guillaume, Dahmani, Ahmed, Raymondie, Chloé, Liot, Géraldine, Gentien, David, Némati, Fariba, Decaudin, Didier, Roman-Roman, Sergio, Schoumacher, Marie
Published 2016

Phase II Trial of Bevacizumab in Combination With Temozolomide as First-Line Treatment in Patients With Metastatic Uveal Melanoma

by Piperno-Neumann, Sophie, Diallo, Alhassane, Etienne-Grimaldi, Marie-Christine, Bidard, François-Clément, Rodrigues, Manuel, Plancher, Corine, Mariani, Pascale, Cassoux, Nathalie, Decaudin, Didier, Asselain, Bernard, Servois, Vincent
Published 2016

Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings

by Bieche, Ivan, Vacher, Sophie, Vallerand, David, Richon, Sophie, Hatem, Rana, De Plater, Ludmilla, Dahmani, Ahmed, Némati, Fariba, Angevin, Eric, Marangoni, Elisabetta, Roman-Roman, Sergio, Decaudin, Didier, Dangles-Marie, Virginie
Published 2014

Targeting Bcl-2/Bcl-XL Induces Antitumor Activity in Uveal Melanoma Patient-Derived Xenografts

by Némati, Fariba, de Montrion, Catherine, Lang, Guillaume, Kraus-Berthier, Laurence, Carita, Guillaume, Sastre-Garau, Xavier, Berniard, Aurélie, Vallerand, David, Geneste, Olivier, de Plater, Ludmilla, Pierré, Alain, Lockhart, Brian, Desjardins, Laurence, Piperno-Neumann, Sophie, Depil, Stéphane, Decaudin, Didier
Published 2014

Upregulation of HLA Expression in Primary Uveal Melanoma by Infiltrating Leukocytes

by van Essen, T. Huibertus, van Pelt, Sake I., Bronkhorst, Inge H. G., Versluis, Mieke, Némati, Fariba, Laurent, Cécile, Luyten, Gregorius P. M., van Hall, Thorbald, van den Elsen, Peter J., van der Velden, Pieter A., Decaudin, Didier, Jager, Martine J.
Published 2016

Dual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma

by Carita, Guillaume, Frisch-Dit-Leitz, Estelle, Dahmani, Ahmed, Raymondie, Chloé, Cassoux, Nathalie, Piperno-Neumann, Sophie, Némati, Fariba, Laurent, Cécile, De Koning, Leanne, Halilovic, Ensar, Jeay, Sebastien, Wylie, Andrew, Emery, Caroline, Roman-Roman, Sergio, Schoumacher, Marie, Decaudin, Didier
Published 2016

Predictive Gene Signature of Response to the Anti-TweakR mAb PDL192 in Patient-Derived Breast Cancer Xenografts

by de Plater, Ludmilla, Vincent-Salomon, Anne, Berger, Frédérique, Nicolas, André, Vacher, Sophie, Gravier, Eléonore, Thuleau, Aurélie, Karboul, Narjesse, Richardson, Marion, Elbaz, Clément, Marangoni, Elisabetta, Bièche, Ivan, Paoletti, Xavier, Roman-Roman, Sergio, Culp, Patricia A., Asselain, Bernard, Diéras, Véronique, Decaudin, Didier
Published 2014

Molecular profiling of patient-derived breast cancer xenografts

by Reyal, Fabien, Guyader, Charlotte, Decraene, Charles, Lucchesi, Carlo, Auger, Nathalie, Assayag, Franck, De Plater, Ludmilla, Gentien, David, Poupon, Marie-France, Cottu, Paul, De Cremoux, Patricia, Gestraud, Pierre, Vincent-Salomon, Anne, Fontaine, Jean-Jacques, Roman-Roman, Sergio, Delattre, Olivier, Decaudin, Didier, Marangoni, Elisabetta
Published 2012

Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

by Legrier, Marie-Emmanuelle, Bièche, Ivan, Gaston, Julie, Beurdeley, Arnaud, Yvonnet, Vanessa, Déas, Olivier, Thuleau, Aurélie, Château-Joubert, Sophie, Servely, Jean-Luc, Vacher, Sophie, Lassalle, Myriam, Depil, Stéphane, C Tucker, Gordon, Fontaine, Jean-Jacques, Poupon, Marie-France, Roman-Roman, Sergio, Judde, Jean-Gabriel, Decaudin, Didier, Cairo, Stefano, Marangoni, Elisabetta
Published 2016

Characterization of Breast Cancer Preclinical Models Reveals a Specific Pattern of Macrophage Polarization

by Vallerand, David, Massonnet, Gérald, Kébir, Fatima, Gentien, David, Maciorowski, Zofia, De la Grange, Pierre, Sigal-Zafrani, Brigitte, Richardson, Marion, Humbert, Sandrine, Thuleau, Aurélie, Assayag, Franck, de Plater, Ludmilla, Nicolas, André, Scholl, Suzy, Marangoni, Elisabetta, Weigand, Stefan, Roman-Roman, Sergio, Savina, Ariel, Decaudin, Didier
Published 2016