FLASH Assembly of TALENs Enables High-Throughput Genome Editing

by Reyon, Deepak, Tsai, Shengdar Q., Khayter, Cyd, Foden, Jennifer A., Sander, Jeffry D., Joung, J. Keith
Published 2012

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

by Fu, Yanfang, Sander, Jeffry D., Reyon, Deepak, Cascio, Vincent M., Joung, J. Keith
Published 2014

Identification of promoter targets of enhancers by epigenetic knockdown using TAL DNA binding proteins

by Mendenhall, Eric M, Williamson, Kaylyn, Reyon, Deepak, Joung, J Keith, Bernstein, Bradley E
Published 2013

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

by Sander, Jeffry D., Cade, Lindsay, Khayter, Cyd, Reyon, Deepak, Peterson, Randall T., Joung, J. Keith, Yeh, Jing-Ruey J.
Published 2011

Robust, synergistic regulation of human gene expression using TALE activators

by Maeder, Morgan L., Linder, Samantha J., Reyon, Deepak, Angstman, James F., Fu, Yanfang, Sander, Jeffry D., Joung, J. Keith
Published 2013

Locus-specific editing of histone modifications at endogenous enhancers using programmable TALE-LSD1 fusions

by Mendenhall, Eric M., Williamson, Kaylyn E., Reyon, Deepak, Zou, James Y., Ram, Oren, Joung, J. Keith, Bernstein, Bradley E.
Published 2013

High frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

by Fu, Yanfang, Foden, Jennifer A., Khayter, Cyd, Maeder, Morgan L., Reyon, Deepak, Joung, J. Keith, Sander, Jeffry D.
Published 2013

Broad Specificity Profiling of TALENs Results in Engineered Nucleases With Improved DNA Cleavage Specificity

by Guilinger, John P., Pattanayak, Vikram, Reyon, Deepak, Tsai, Shengdar Q., Sander, Jeffry D., Joung, J. Keith, Liu, David R.
Published 2014

Context influences on TALE–DNA binding revealed by quantitative profiling

by Rogers, Julia M., Barrera, Luis A., Reyon, Deepak, Sander, Jeffry D., Kellis, Manolis, Joung, J Keith, Bulyk, Martha L.
Published 2015

Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)

by Moore, Finola E., Reyon, Deepak, Sander, Jeffry D., Martinez, Sarah A., Blackburn, Jessica S., Khayter, Cyd, Ramirez, Cherie L., Joung, J. Keith, Langenau, David M.
Published 2012

Highly efficient generation of heritable zebrafish gene mutations using homo- and heterodimeric TALENs

by Cade, Lindsay, Reyon, Deepak, Hwang, Woong Y., Tsai, Shengdar Q., Patel, Samir, Khayter, Cyd, Joung, J. Keith, Sander, Jeffry D., Peterson, Randall T., Yeh, Jing-Ruey Joanna
Published 2012

Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System

by Hwang, Woong Y., Fu, Yanfang, Reyon, Deepak, Maeder, Morgan L., Kaini, Prakriti, Sander, Jeffry D., Joung, J. Keith, Peterson, Randall T., Yeh, Jing-Ruey Joanna
Published 2013

Efficient In Vivo Genome Editing Using RNA-Guided Nucleases

by Hwang, Woong Y., Fu, Yanfang, Reyon, Deepak, Maeder, Morgan L., Tsai, Shengdar Q., Sander, Jeffry D., Peterson, Randall T., Yeh, J.-R. Joanna, Joung, J. Keith
Published 2013

Targeted Deletion and Inversion of Tandemly Arrayed Genes in Arabidopsis thaliana Using Zinc Finger Nucleases

by Qi, Yiping, Li, Xiaohong, Zhang, Yong, Starker, Colby G., Baltes, Nicholas J., Zhang, Feng, Sander, Jeffry D., Reyon, Deepak, Joung, J. Keith, Voytas, Daniel F.
Published 2013

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

by Tsai, Shengdar Q., Wyvekens, Nicolas, Khayter, Cyd, Foden, Jennifer A., Thapar, Vishal, Reyon, Deepak, Goodwin, Mathew J., Aryee, Martin J., Joung, J. Keith
Published 2014

Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences

by Sander, Jeffry D, Reyon, Deepak, Maeder, Morgan L, Foley, Jonathan E, Thibodeau-Beganny, Stacey, Li, Xiaohong, Regan, Maureen R, Dahlborg, Elizabeth J, Goodwin, Mathew J, Fu, Fengli, Voytas, Daniel F, Joung, J Keith, Dobbs, Drena
Published 2010

Targeted DNA Demethylation and Endogenous Gene Activation Using Programmable TALE-TET1 Fusions

by Maeder, Morgan L, Angstman, James F, Richardson, Marcy E, Linder, Samantha J, Cascio, Vincent M, Tsai, Shengdar Q, Ho, Quan H, Sander, Jeffry D, Reyon, Deepak, Bernstein, Bradley E, Costello, Joseph F, Wilkinson, Miles F, Joung, J Keith
Published 2013

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites

by Sander, Jeffry D., Ramirez, Cherie L., Linder, Samantha J., Pattanayak, Vikram, Shoresh, Noam, Ku, Manching, Foden, Jennifer A., Reyon, Deepak, Bernstein, Bradley E., Liu, David R., Joung, J. Keith
Published 2013

Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells

by Liao, Jing, Karnik, Rahul, Gu, Hongcang, Ziller, Michael J., Clement, Kendell, Tsankov, Alexander M., Akopian, Veronika, Gifford, Casey A., Donaghey, Julie, Galonska, Christina, Pop, Ramona, Reyon, Deepak, Tsai, Shengdar Q., Mallard, William, Joung, J. Keith, Rinn, John L., Gnirke, Andreas, Meissner, Alexander
Published 2015