Reassessing target antigens for adoptive T cell therapy

by Hinrichs, Christian S., Restifo, Nicholas P.
Published 2013

Inhibition of the T cell oxygen sensing machinery promotes anti-tumor efficacy

by Clever, David, Roychoudhuri, Rahul, Restifo, Nicholas P
Published 2015

Predominant Role for Directly Transfected Dendritic Cells in Antigen Presentation to CD8+ T Cells after Gene Gun Immunization

by Porgador, Angel, Irvine, Kari R., Iwasaki, Akiko, Barber, Brian H., Restifo, Nicholas P., Germain, Ronald N.
Published 1998

Mining the mutanome: developing highly personalized Immunotherapies based on mutational analysis of tumors

by Overwijk, Willem W, Wang, Ena, Marincola, Francesco M, Rammensee, Hans-Georg, Restifo, Nicholas P
Published 2013

Tumor-specific CD4+ T cells maintain effector and memory tumor-specific CD8+ T cells

by Church, Sarah E, Jensen, Shawn M, Antony, Paul A, Restifo, Nicholas P, Fox, Bernard A
Published 2014

Cish attenuates proximal TCR-signaling and CD8+ T cell immunity

by Palmer, Douglas, Guittard, Geoffery, Patel, Shashank, Samelson, Lawrence E, Restifo, Nicholas P
Published 2014

Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia

by Tran, Eric, Chinnasamy, Dhanalakshmi, Yu, Zhiya, Morgan, Richard A., Lee, Chyi-Chia Richard, Restifo, Nicholas P., Rosenberg, Steven A.
Published 2013

Immune Evasion by Murine Melanoma Mediated through CC Chemokine Receptor-10

by Murakami, Takashi, Cardones, Adela R., Finkelstein, Steven E., Restifo, Nicholas P., Klaunberg, Brenda A., Nestle, Frank O., Castillo, S. Sianna, Dennis, Phillip A., Hwang, Sam T.
Published 2003

Self-Tolerance to the Murine Homologue of a Tyrosinase-Derived Melanoma Antigen: Implications for Tumor Immunotherapy

by Colella, Teresa A., Bullock, Timothy N.J., Russell, Liane B., Mullins, David W., Overwijk, Willem W., Luckey, Chance John, Pierce, Richard A., Restifo, Nicholas P., Engelhard, Victor H.
Published 2000

Induction of an acute vitamin A-deficient state following total body irradiation impairs anti-tumor immunity by altering the homeostasis of pre-cDC derived dendritic cells

by Klebanoff, Christopher A, Spencer, Sean, Roychoudhuri, Rahu, Ji, Yun, Sukumar, Madhu, Muranski, Pawel, Napoli, Joseph L, Gattinoni, Luca, Belkaid, Yasmine, Restifo, Nicholas P
Published 2013

Identification of the Genomic Insertion Site of Pmel-1 TCR α and β Transgenes by Next-Generation Sequencing

by Ji, Yun, Abrams, Natalie, Zhu, Wei, Salinas, Eddie, Yu, Zhiya, Palmer, Douglas C., Jailwala, Parthav, Franco, Zulmarie, Roychoudhuri, Rahul, Stahlberg, Eric, Gattinoni, Luca, Restifo, Nicholas P.
Published 2014

Toll-like receptor agonist therapy can profoundly augment the antitumor activity of adoptively transferred CD8+ T cells without host preconditioning

by Nelson, Michelle H., Bowers, Jacob S., Bailey, Stefanie R., Diven, Marshall A., Fugle, Caroline W., Kaiser, Andrew D. M., Wrzesinski, Claudia, Liu, Bei, Restifo, Nicholas P., Paulos, Chrystal M.
Published 2016

Elevated potassium levels suppress T cell activation within tumors

by Eil, Robert L, Roychoudhuri, Rahul, Clever, David, Patel, Shashank, Sukumar, Madhu, Pan, Jenny H, Palmer, Douglas, Klebanoff, Christopher A, Restifo, Nicholas P
Published 2015

Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits CD8+ T cell memory formation

by Ji, Yun, Pos, Zoltan, Rao, Mahadev, Klebanoff, Christopher A., Yu, Zhiya, Sukumar, Madhusudhanan, Reger, Robert N., Palmer, Douglas C., Borman, Zachary A., Muranski, Pawel, Wang, Ena, Schrump, David S., Marincola, Francesco M., Restifo, Nicholas P., Gattinoni, Luca
Published 2011

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

by Gattinoni, Luca, Finkelstein, Steven E., Klebanoff, Christopher A., Antony, Paul A., Palmer, Douglas C., Spiess, Paul J., Hwang, Leroy N., Yu, Zhiya, Wrzesinski, Claudia, Heimann, David M., Surh, Charles D., Rosenberg, Steven A., Restifo, Nicholas P.
Published 2005

Elucidating the Autoimmune and Antitumor Effector Mechanisms of a Treatment Based on Cytotoxic T Lymphocyte Antigen-4 Blockade in Combination with a B16 Melanoma Vaccine: Compariso...

by van Elsas, Andrea, Sutmuller, Roger P.M., Hurwitz, Arthur A., Ziskin, Jennifer, Villasenor, Jennifer, Medema, Jan-Paul, Overwijk, Willem W., Restifo, Nicholas P., Melief, Cornelis J.M., Offringa, Rienk, Allison, James P.
Published 2001

gp100/pmel 17 Is a Murine Tumor Rejection Antigen: Induction of “Self”-reactive, Tumoricidal T Cells Using High-affinity, Altered Peptide Ligand

by Overwijk, Willem W., Tsung, Allan, Irvine, Kari R., Parkhurst, Maria R., Goletz, Theresa J., Tsung, Kangla, Carroll, Miles W., Liu, Chunlei, Moss, Bernard, Rosenberg, Steven A., Restifo, Nicholas P.
Published 1998

Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function

by Zeng, Rong, Spolski, Rosanne, Finkelstein, Steven E., Oh, SangKon, Kovanen, Panu E., Hinrichs, Christian S., Pise-Masison, Cynthia A., Radonovich, Michael F., Brady, John N., Restifo, Nicholas P., Berzofsky, Jay A., Leonard, Warren J.
Published 2005

BACH2 represses effector programmes to stabilize Treg-mediated immune homeostasis - a new target in tumor immunotherapy?

by Roychoudhuri, Rahul, Hirahara, Kiyoshi, Mousavi, Kambiz, Clever, David, Bonelli, Michael, Klebanoff, Christopher, Sartorelli, Vittorio, Kanno, Yuka, Gattinoni, Luca, Wang, Ena, Liu, Hui, Marincola, Franco, Kazuhiko, Igarashi, O’Shea, John, Restifo, Nicholas P
Published 2013

T cell receptor affinity and avidity defines antitumor response and autoimmunity in T cell immunotherapy

by Krogsgaard, Michelle, Zhong, Shi, Malecek, Karolina, Johnson, Laura A, Yu, Zhiya, Vega-Saenz de Miera, Eleazar, Darvishian, Farbod, McGary-Shipper, Katelyn, Huang, Kevin, Boyer, Joshua, Corse, Emily, Shao, Yongzhao, Rosenberg, Steven A, Restifo, Nicholas P, Osman, Iman
Published 2013