Reassessing target antigens for adoptive T cell therapy

Adoptive T cell therapy can target and kill widespread malignant cells thereby inducing durable clinical responses in melanoma and selected other malignances. However, many commonly targeted tumor antigens are also expressed by healthy tissues, and T cells do not distinguish between benign and malig...

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Bibliographic Details
Main Authors: Hinrichs, Christian S., Restifo, Nicholas P.
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280065/