Evaluation of blood-brain barrier transport and CNS drug metabolism in diseased and control brain after intravenous L-DOPA in a unilateral rat model of Parkinson's disease

by Ravenstijn, Paulien GM, Drenth, Henk-Jan, O'Neill, Michael J, Danhof, Meindert, de Lange, Elizabeth CM
Published 2012

Identification of a novel imprinting mechanism at the X-linked imprinted locus, X-linked Lymphocyte Regulated 3/4 (Xlr3/4)

by Qureshi, Sohaib M, Murphy, Michael B, Kasowitz, Seth, Foley, Robert J, O’Neill, Michael J
Published 2013

Identification of a Recently Active Mammalian SINE Derived from Ribosomal RNA

by Longo, Mark S., Brown, Judy D., Zhang, Chu, O’Neill, Michael J., O’Neill, Rachel J.
Published 2015

Determination of dosage compensation of the mammalian X chromosome by RNA-seq is dependent on analytical approach

by Jue, Nathaniel K, Murphy, Michael B, Kasowitz, Seth D, Qureshi, Sohaib M, Obergfell, Craig J, Elsisi, Sahar, Foley, Robert J, O’Neill, Rachel J, O’Neill, Michael J
Published 2013

CNS SIRT3 Expression Is Altered by Reactive Oxygen Species and in Alzheimer’s Disease

by Weir, Heather J. M., Murray, Tracey K., Kehoe, Patrick G., Love, Seth, Verdin, Eric M., O’Neill, Michael J., Lane, Jon D., Balthasar, Nina
Published 2012

Rapid Evolutionary Rates and Unique Genomic Signatures Discovered in the First Reference Genome for the Southern Ocean Salp, Salpa thompsoni (Urochordata, Thaliacea)

by Jue, Nathaniel K., Batta-Lona, Paola G., Trusiak, Sarah, Obergfell, Craig, Bucklin, Ann, O’Neill, Michael J., O’Neill, Rachel J.
Published 2016

Critical residues involved in tau binding to fyn: implications for tau phosphorylation in Alzheimer’s disease

by Lau, Dawn H. W., Hogseth, Marte, Phillips, Emma C., O’Neill, Michael J., Pooler, Amy M., Noble, Wendy, Hanger, Diane P.
Published 2016

Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer’s disease brain

by Kurbatskaya, Ksenia, Phillips, Emma C., Croft, Cara L., Dentoni, Giacomo, Hughes, Martina M., Wade, Matthew A., Al-Sarraj, Safa, Troakes, Claire, O’Neill, Michael J., Perez-Nievas, Beatriz G., Hanger, Diane P., Noble, Wendy
Published 2016

A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity

by Ahmed, Zeshan, Cooper, Jane, Murray, Tracey K., Garn, Katya, McNaughton, Emily, Clarke, Hannah, Parhizkar, Samira, Ward, Mark A., Cavallini, Annalisa, Jackson, Samuel, Bose, Suchira, Clavaguera, Florence, Tolnay, Markus, Lavenir, Isabelle, Goedert, Michel, Hutton, Michael L., O’Neill, Michael J.
Published 2014

Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates

by Falcon, Benjamin, Cavallini, Annalisa, Angers, Rachel, Glover, Sarah, Murray, Tracey K., Barnham, Luanda, Jackson, Samuel, O'Neill, Michael J., Isaacs, Adrian M., Hutton, Michael L., Szekeres, Philip G., Goedert, Michel, Bose, Suchira
Published 2015

Imaging the accumulation and suppression of tau pathology using multiparametric MRI

by Holmes, Holly E., Colgan, Niall, Ismail, Ozama, Ma, Da, Powell, Nick M., O'Callaghan, James M., Harrison, Ian F., Johnson, Ross A., Murray, Tracey K., Ahmed, Zeshan, Heggenes, Morton, Fisher, Alice, Cardoso, M.J., Modat, Marc, Walker-Samuel, Simon, Fisher, Elizabeth M.C., Ourselin, Sebastien, O'Neill, Michael J., Wells, Jack A., Collins, Emily C., Lythgoe, Mark F.
Published 2016

Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-in...

by Keatinge, Marcus, Bui, Hai, Menke, Aswin, Chen, Yu-Chia, Sokol, Anna M., Bai, Qing, Ellett, Felix, Da Costa, Marc, Burke, Derek, Gegg, Matthew, Trollope, Lisa, Payne, Thomas, McTighe, Aimee, Mortiboys, Heather, de Jager, Sarah, Nuthall, Hugh, Kuo, Ming-Shang, Fleming, Angeleen, Schapira, Anthony H.V., Renshaw, Stephen A., Highley, J. Robin, Chacinska, Agnieszka, Panula, Pertti, Burton, Edward A., O'Neill, Michael J., Bandmann, Oliver
Published 2015

The IMPROVE guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

by Percie du Sert, Nathalie, Alfieri, Alessio, Allan, Stuart M., Carswell, Hilary V.O., Deuchar, Graeme A., Farr, Tracy D., Flecknell, Paul, Gallagher, Lindsay, Gibson, Claire L., Haley, Michael J., Macleod, Malcolm R., McColl, Barry W., McCabe, Christopher, Morancho, Anna, Moon, Lawrence D.F., O’Neill, Michael J., Pérez de Puig, Isabel, Planas, Anna, Ragan, C. Ian, Rosell, Anna, Roy, Lisa A., Ryder, Kathryn O., Simats, Alba, Sena, Emily S., Sutherland, Brad A., Tricklebank, Mark D., Trueman, Rebecca C., Whitfield, Lucy, Wong, Raymond, Macrae, I. Mhairi
Published 2017