RUNX Family Participates in the Regulation of p53-Dependent DNA Damage Response

by Ozaki, Toshinori, Nakagawara, Akira, Nagase, Hiroki
Published 2013

New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK

by Fujiwara, Kyoko, Igarashi, Jun, Irahara, Natsumi, Kimura, Makoto, Nagase, Hiroki
Published 2007

A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts

by Pandian, Ganesh N., Nakano, Yusuke, Sato, Shinsuke, Morinaga, Hironobu, Bando, Toshikazu, Nagase, Hiroki, Sugiyama, Hiroshi
Published 2012

DNA hypermethylation of zygote arrest 1 (ZAR1) in hepatitis C virus positive related hepatocellular carcinoma

by Takagi, Keiko, Fujiwara, Kyoko, Takayama, Tadatoshi, Mamiya, Takao, Soma, Masayoshi, Nagase, Hiroki
Published 2013

Unfavorable neuroblastoma prognostic factor NLRR2 inhibits cell differentiation by transcriptional induction through JNK pathway

by Sheikh, Afzal, Takatori, Atsushi, Hossain, Md Shamim, Hasan, Md Kamrul, Tagawa, Masatoshi, Nagase, Hiroki, Nakagawara, Akira
Published 2016

Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity

by Ozaki, Toshinori, Sugimoto, Hirokazu, Nakamura, Mizuyo, Hiraoka, Kiriko, Yoda, Hiroyuki, Sang, Meixiang, Fujiwara, Kyoko, Nagase, Hiroki
Published 2015

Quantitation of Pyrrole-Imidazole Polyamide in Rat Plasma by High-Performance Liquid Chromatography Coupled with UV Detection

by Kamei, Tomonori, Aoyama, Takahiko, Tanaka, Chihiro, Nagashima, Takafumi, Aoyama, Yukio, Hayashi, Hiroyuki, Nagase, Hiroki, Ueno, Takahiro, Fukuda, Noboru, Matsumoto, Yoshiaki
Published 2012

Genome-wide survey reveals dynamic widespread tissue-specific changes in DNA methylation during development

by Liang, Ping, Song, Fei, Ghosh, Srimoyee, Morien, Evan, Qin, Maochun, Mahmood, Saleh, Fujiwara, Kyoko, Igarashi, Jun, Nagase, Hiroki, Held, William A
Published 2011

NR4A3, a possibile oncogenic factor for neuroblastoma associated with CpGi methylation within the third exon

by UEKUSA, SHOTA, KAWASHIMA, HIROYUKI, SUGITO, KIMINOBU, YOSHIZAWA, SHINSUKE, SHINOJIMA, YUI, IGARASHI, JUN, GHOSH, SRIMOYEE, WANG, XAOFEI, FUJIWARA, KYOKO, IKEDA, TARO, KOSHINAGA, TSUGUMICHI, SOMA, MASAYOSHI, NAGASE, HIROKI
Published 2014

Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts

by Pandian, Ganesh N., Taniguchi, Junichi, Junetha, Syed, Sato, Shinsuke, Han, Le, Saha, Abhijit, AnandhaKumar, Chandran, Bando, Toshikazu, Nagase, Hiroki, Vaijayanthi, Thangavel, Taylor, Rhys D., Sugiyama, Hiroshi
Published 2014

Identification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer Genome

by Lin, Jason, Hiraoka, Kiriko, Watanabe, Takayoshi, Kuo, Tony, Shinozaki, Yoshinao, Takatori, Atsushi, Koshikawa, Nobuko, Chandran, Anandhakumar, Otsuki, Joe, Sugiyama, Hiroshi, Horton, Paul, Nagase, Hiroki
Published 2016

Genetic architecture of murine skin inflammation and tumor susceptibility

by Quigley, David A., To, Minh D., Pérez-Losada, Jesús, Pelorosso, Facundo G., Mao, Jian-Hua, Nagase, Hiroki, Ginzinger, David G., Balmain, Allan
Published 2009

Oncogenic Lmo3 cooperates with Hen2 to induce hydrocephalus in mice

by Isogai, Eriko, Okumura, Kazuhiro, Saito, Megumi, Yoshizawa, Yasuhiro, Itoh, Kyoko, Tando, So, Ohira, Miki, Haraguchi, Seiki, Nakagawara, Akira, Fushiki, Shinji, Nagase, Hiroki, Wakabayashi, Yuichi
Published 2015

Inhibition of malignant phenotypes of human osteosarcoma cells by a gene silencer, a pyrrole–imidazole polyamide, which targets an E-box motif

by Taniguchi, Masashi, Fujiwara, Kyoko, Nakai, Yuji, Ozaki, Toshinori, Koshikawa, Nobuko, Toshio, Kojima, Kataba, Motoaki, Oguni, Asako, Matsuda, Hiroyuki, Yoshida, Yukihiro, Tokuhashi, Yasuaki, Fukuda, Noboru, Ueno, Takahiro, Soma, Masayoshi, Nagase, Hiroki
Published 2014

Pyrrole-imidazole polyamide targeted to break fusion sites in TMPRSS2 and ERG gene fusion represses prostate tumor growth

by Obinata, Daisuke, Ito, Akiko, Fujiwara, Kyoko, Takayama, Ken-Ichi, Ashikari, Daisaku, Murata, Yasutaka, Yamaguchi, Kenya, Urano, Tomohiko, Fujimura, Tetsuya, Fukuda, Noboru, Soma, Masayoshi, Watanabe, Takayoshi, Nagase, Hiroki, Inoue, Satoshi, Takahashi, Satoru
Published 2014

Preclinical Study of Novel Gene Silencer Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Hypertrophic Scars in a Common Marmoset Primate Model

by Igarashi, Jun, Fukuda, Noboru, Inoue, Takashi, Nakai, Shigeki, Saito, Kosuke, Fujiwara, Kyoko, Matsuda, Hiroyuki, Ueno, Takahiro, Matsumoto, Yoshiaki, Watanabe, Takayoshi, Nagase, Hiroki, Bando, Toshikazu, Sugiyama, Hiroshi, Itoh, Toshio, Soma, Masayoshi
Published 2015

Identification of a novel E-box binding pyrrole-imidazole polyamide inhibiting MYC-driven cell proliferation

by Mishra, Rajeev, Watanabe, Takayoshi, Kimura, Makoto T, Koshikawa, Nobuko, Ikeda, Maki, Uekusa, Shota, Kawashima, Hiroyuki, Wang, Xiaofei, Igarashi, Jun, Choudhury, Diptiman, Grandori, Carla, Kemp, Christopher J, Ohira, Miki, Verma, Narendra K, Kobayashi, Yujin, Takeuchi, Jin, Koshinaga, Tsugumichi, Nemoto, Norimichi, Fukuda, Noboru, Soma, Masayoshi, Kusafuka, Takeshi, Fujiwara, Kyoko, Nagase, Hiroki
Published 2015