Dietary supplementation with Lovaza and krill oil shortens the life span of long-lived F1 mice

by Spindler, Stephen R., Mote, Patricia L., Flegal, James M.
Published 2014

Deep sequencing identifies circulating mouse miRNAs that are functionally implicated in manifestations of aging and responsive to calorie restriction

by Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Yamakawa, Amy, Guerrero, Noel, Boffelli, Dario, Mote, Patricia, Martin, David IK
Published 2013

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

by Dhahbi, Joseph M, Spindler, Stephen R, Atamna, Hani, Yamakawa, Amy, Boffelli, Dario, Mote, Patricia, Martin, David IK
Published 2013

MicroRNAs Circulate in the Hemolymph of Drosophila and Accumulate Relative to Tissue microRNAs in an Age-Dependent Manner

by Dhahbi, Joseph M., Atamna, Hani, Li, Rui, Yamakawa, Amy, Guerrero, Noel, Lam, Hanh T., Mote, Patricia, Spindler, Stephen R.
Published 2016

Nordihydroguaiaretic Acid Extends the Lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters Energy Homeostasis in Mice

by Spindler, Stephen R., Mote, Patricia L., Lublin, Alex L., Flegal, James M., Dhahbi, Joseph M., Li, Rui
Published 2015

Statin Treatment Increases Lifespan and Improves Cardiac Health in Drosophila by Decreasing Specific Protein Prenylation

by Spindler, Stephen R., Li, Rui, Dhahbi, Joseph M., Yamakawa, Amy, Mote, Patricia, Bodmer, Rolf, Ocorr, Karen, Williams, Renee T., Wang, Yinsheng, Ablao, Kenneth P.
Published 2012

Metformin improves healthspan and lifespan in mice

by Martin-Montalvo, Alejandro, Mercken, Evi M., Mitchell, Sarah J., Palacios, Hector H., Mote, Patricia L., Scheibye-Knudsen, Morten, Gomes, Ana P., Ward, Theresa M., Minor, Robin K., Blouin, Marie-José, Schwab, Matthias, Pollak, Michael, Zhang, Yongqing, Yu, Yinbing, Becker, Kevin G., Bohr, Vilhelm A., Ingram, Donald K., Sinclair, David A., Wolf, Norman S., Spindler, Stephen R., Bernier, Michel, de Cabo, Rafael
Published 2013