High-throughput approaches to discover novel immunomodulatory agents for cancer

by McMillin, Douglas W., Mitsiades, Constantine S.
Published 2012

Microenvironmental Influence on Pre-Clinical Activity of Polo-Like Kinase Inhibition in Multiple Myeloma: Implications for Clinical Translation

by McMillin, Douglas W., Delmore, Jake, Negri, Joseph, Ooi, Melissa, Klippel, Steffen, Miduturu, Chandrasekhar V., Gray, Nathanael S., Richardson, Paul G., Anderson, Kenneth C., Kung, Andrew L., Mitsiades, Constantine S.
Published 2011

The Medical Research Council Myeloma IX trial: the impact on treatment paradigms*

by Richardson, Paul G, Laubach, Jacob P, Schlossman, Robert L, Ghobrial, Irene M, Mitsiades, Constantine S, Rosenblatt, Jacalyn, Mahindra, Anuj, Raje, Noopur, Munshi, Nikhil, Anderson, Kenneth C
Published 2012

Stem Cell Implants for Cancer Therapy: TRAIL-Expressing Mesenchymal Stem Cells Target Cancer Cells In Situ

by Reagan, Michaela R., Seib, F. Philipp, McMillin, Douglas W., Sage, Elizabeth K., Mitsiades, Constantine S., Janes, Sam M., Ghobrial, Irene M., Kaplan, David L.
Published 2012

Identification of proteins found to be significantly altered when comparing the serum proteome from Multiple Myeloma patients with varying degrees of bone disease

by Dowling, Paul, Hayes, Catriona, Ting, Kay Reen, Hameed, Abdul, Meiller, Justine, Mitsiades, Constantine, Anderson, Kenneth C, Clynes, Martin, Clarke, Colin, Richardson, Paul, O’Gorman, Peter
Published 2014

Lenalidomide for the treatment of relapsed and refractory multiple myeloma

by van de Donk, Niels WCJ, Görgün, Güllü, Groen, Richard WJ, Jakubikova, Jana, Mitsiades, Constantine S, Hideshima, Teru, Laubach, Jacob, Nijhof, Inger S, Raymakers, Reinier A, Lokhorst, Henk M, Richardson, Paul G, Anderson, Kenneth C
Published 2012

Selective Akt Inhibitors Synergize with Tyrosine Kinase Inhibitors and Effectively Override Stroma-Associated Cytoprotection of Mutant FLT3-Positive AML Cells

by Weisberg, Ellen, Liu, Qingsong, Zhang, Xin, Nelson, Erik, Sattler, Martin, Liu, Feiyang, Nicolais, Maria, Zhang, Jianming, Mitsiades, Constantine, Smith, Robert W., Stone, Richard, Galinsky, Ilene, Nonami, Atsushi, Griffin, James D., Gray, Nathanael
Published 2013

Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anti-cancer drug activity

by McMillin, Douglas W., Delmore, Jake, Weisberg, Ellen, Negri, Joseph M., Geer, D. Corey, Klippel, Steffen, Mitsiades, Nicholas, Schlossman, Robert L., Munshi, Nikhil C., Kung, Andrew L., Griffin, James D., Richardson, Paul G., Anderson, Kenneth C., Mitsiades, Constantine S.
Published 2010

Discovery of a Potent, Covalent BTK Inhibitor for B-Cell Lymphoma

by Wu, Hong, Wang, Wenchao, Liu, Feiyang, Weisberg, Ellen L., Tian, Bei, Chen, Yongfei, Li, Binhua, Wang, Aoli, Wang, Beilei, Zhao, Zheng, McMillin, Douglas W., Hu, Chen, Li, Hong, Wang, Jinhua, Liang, Yanke, Buhrlage, Sara J., Liang, Junting, Liu, Jing, Yang, Guang, Brown, Jennifer R., Treon, Steven P., Mitsiades, Constantine S., Griffin, James D., Liu, Qingsong, Gray, Nathanael S.
Published 2014

The Cyclophilin A-CD147 complex promotes bone marrow colonization of B-cell malignancies: implications for therapy

by Zhu, Di, Wang, Zhongqiu, Zhao, Jian-Jun, Calimeri, Teresa, Meng, Jiang, Hideshima, Teru, Fulciniti, Mariateresa, Kang, Yue, Ficarro, Scott, Tai, Yu-Tzu, Hunter, Zachary, McMilin, Douglas, Tong, Haoxuan, Mitsiades, Constantine S., Wu, Catherine, Treon, Steven, Dorfman, David M., Pinkus, Geraldine, Munshi, Nikhil, Tassone, Pierfrancesco, Marto, Jarrod, Anderson, Kenneth, Carrasco, Ruben D.
Published 2015

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

by Kwiatkowski, Nicholas, Zhang, Tinghu, Rahl, Peter B, Abraham, Brian J, Reddy, Jessica, Ficarro, Scott B, Dastur, Anahita, Amzallag, Arnaud, Ramaswamy, Sridhar, Tesar, Bethany, Jenkins, Christopher R, Hannett, Nancy M, McMillin, Douglas, Sanda, Takaomi, Sim, Taebo, Kim, Nam Doo, Look, Thomas, Mitsiades, Constantine, Weng, Andrew P, Brown, Jennifer R, Benes, Cyril H., Marto, Jarrod A, Young, Richard A, Gray, Nathanael S.
Published 2014

An epigenomic approach to therapy for tamoxifen-resistant breast cancer

by Feng, Qin, Zhang, Zheng, Shea, Martin J, Creighton, Chad J, Coarfa, Cristian, Hilsenbeck, Susan G, Lanz, Rainer, He, Bin, Wang, Lei, Fu, Xiaoyong, Nardone, Agostina, Song, Yongcheng, Bradner, James, Mitsiades, Nicholas, Mitsiades, Constantine S, Osborne, C Kent, Schiff, Rachel, O'Malley, Bert W
Published 2014