Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

by Watterson, Kenneth R., Bestow, Dawn, Gallagher, Jennifer, Hamilton, D. Lee, Ashford, Fiona B., Meakin, Paul J., Ashford, Michael L.J.
Published 2012

Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes

by Hamilton, D. Lee, Findlay, John A., Montagut, Gemma, Meakin, Paul J., Bestow, Dawn, Jalicy, Susan M., Ashford, Michael L. J.
Published 2014

Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation

by Meakin, Paul J., Morrison, Vicky L., Sneddon, Claire C., Savinko, Terhi, Uotila, Liisa, Jalicy, Susan M., Gabriel, Jennie L., Kang, Li, Ashford, Michael L. J., Fagerholm, Susanna C.
Published 2015

Reduction in BACE1 decreases body weight, protects against diet-induced obesity and enhances insulin sensitivity in mice

by Meakin, Paul J., Harper, Alex J., Hamilton, D. Lee, Gallagher, Jennifer, McNeilly, Alison D., Burgess, Laura A., Vaanholt, Lobke M., Bannon, Kirsten A., Latcham, Judy, Hussain, Ishrut, Speakman, John R., Howlett, David R., Ashford, Michael L.J.
Published 2011

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter...

by Rzepecka, Justyna, Pineda, Miguel A., Al-Riyami, Lamyaa, Rodgers, David T., Huggan, Judith K., Lumb, Felicity E., Khalaf, Abedawn I., Meakin, Paul J., Corbet, Marlene, Ashford, Michael L., Suckling, Colin J., Harnett, Margaret M., Harnett, William
Published 2015

Susceptibility of Nrf2-Null Mice to Steatohepatitis and Cirrhosis upon Consumption of a High-Fat Diet Is Associated with Oxidative Stress, Perturbation of the Unfolded Protein Resp...

by Meakin, Paul J., Chowdhry, Sudhir, Sharma, Ritu S., Ashford, Fiona B., Walsh, Shaun V., McCrimmon, Rory J., Dinkova-Kostova, Albena T., Dillon, John F., Hayes, John D., Ashford, Michael L. J.
Published 2014

Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

by McGuire, Victoria A., Ruiz-Zorrilla Diez, Tamara, Emmerich, Christoph H., Strickson, Sam, Ritorto, Maria Stella, Sutavani, Ruhcha V., Weiβ, Anne, Houslay, Kirsty F., Knebel, Axel, Meakin, Paul J., Phair, Iain R., Ashford, Michael L. J., Trost, Matthias, Arthur, J. Simon C.
Published 2016

Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2

by Bell, Karen F.S., Al-Mubarak, Bashayer, Martel, Marc-André, McKay, Sean, Wheelan, Nicola, Hasel, Philip, Márkus, Nóra M., Baxter, Paul, Deighton, Ruth F., Serio, Andrea, Bilican, Bilada, Chowdhry, Sudhir, Meakin, Paul J., Ashford, Michael L.J., Wyllie, David J.A., Scannevin, Robert H., Chandran, Siddharthan, Hayes, John D., Hardingham, Giles E.
Published 2015

Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology

by Horsburgh, Karen, Wardlaw, Joanna M., van Agtmael, Tom, Allan, Stuart M., Ashford, Mike L.J., Bath, Philip M., Brown, Rosalind, Berwick, Jason, Cader, M. Zameel, Carare, Roxana O., Davis, John B., Duncombe, Jessica, Farr, Tracy D., Fowler, Jill H., Goense, Jozien, Granata, Alessandra, Hall, Catherine N., Hainsworth, Atticus H., Harvey, Adam, Hawkes, Cheryl A., Joutel, Anne, Kalaria, Rajesh N., Kehoe, Patrick G., Lawrence, Catherine B., Lockhart, Andy, Love, Seth, Macleod, Malcolm R., Macrae, I. Mhairi, Markus, Hugh S., McCabe, Chris, McColl, Barry W., Meakin, Paul J., Miller, Alyson, Nedergaard, Maiken, O'Sullivan, Michael, Quinn, Terry J., Rajani, Rikesh, Saksida, Lisa M., Smith, Colin, Smith, Kenneth J., Touyz, Rhian M., Trueman, Rebecca C., Wang, Tao, Williams, Anna, Williams, Steven C.R., Work, Lorraine M.
Published 2018