Multiplexing of receptor occupancy measurements for pharmacodynamic biomarker assessment of biopharmaceuticals

by Vainshtein, Inna, Schneider, Amy K., Sun, Bo, Schwickart, Martin, Roskos, Lorin K., Liang, Meina
Published 2015

Characterization, dissolution and solubility of the hydroxypyromorphite–hydroxyapatite solid solution [(PbxCa1−x)5(PO4)3OH] at 25 °C and pH 2–9

by Zhu, Yinian, Huang, Bin, Zhu, Zongqiang, Liu, Huili, Huang, Yanhua, Zhao, Xin, Liang, Meina
Published 2016

Quantitative Measurement of the Target-Mediated Internalization Kinetics of Biopharmaceuticals

by Vainshtein, Inna, Roskos, Lorin K., Cheng, Jackie, Sleeman, Matthew A., Wang, Bing, Liang, Meina
Published 2014

Receptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical development

by Liang, Meina, Schwickart, Martin, Schneider, Amy K., Vainshtein, Inna, Del Nagro, Christopher, Standifer, Nathan, Roskos, Lorin K.
Published 2015

A phase I dose-escalation study of MEDI-575, a PDGFRα monoclonal antibody, in adults with advanced solid tumors

by Becerra, Carlos R., Conkling, Paul, Vogelzang, Nicholas, Wu, Hilary, Hong, Shengyan, Narwal, Rajesh, Liang, Meina, Tavakkoli, Fatemeh, Pandya, Naimish
Published 2014

Evaluation of assay interference and interpretation of CXCR4 receptor occupancy results in a preclinical study with MEDI3185, a fully human antibody to CXCR4

by Schwickart, Martin, Chavez, Carlos, Henderson, Simon, Vainshtein, Inna, Standifer, Nathan, DelNagro, Christopher, Mehrzai, Freshta, Schneider, Amy, Roskos, Lorin, Liang, Meina
Published 2015

Safety and disease response to MEDI-551, an anti-CD19 antibody, in chronic lymphocytic leukemia patients previously treated with rituximab

by Forero, Andres, Hamadani, Mehdi, Kipps, Thomas, Fanale, Michelle, Cuneo, Antonio, Perez de Oteyza, Jaime, Gladstone, Douglas, Andre, Marc, Bellam, Naresh, Goswami, Trishna, Ibrahim, Ramy, Schneider, Amy, Liang, Meina, Eck, Steven, Elgeioushi, Nairouz, Herbst, Ronald, Cheson, Bruce D
Published 2013