Subcutaneous versus Intravenous Administration of Rituximab: Pharmacokinetics, CD20 Target Coverage and B-Cell Depletion in Cynomolgus Monkeys

by Mao, Cheng-Ping, Brovarney, Martin R., Dabbagh, Karim, Birnböck, Herbert F., Richter, Wolfgang F., Del Nagro, Christopher J.
Published 2013

Receptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical development

by Liang, Meina, Schwickart, Martin, Schneider, Amy K., Vainshtein, Inna, Del Nagro, Christopher, Standifer, Nathan, Roskos, Lorin K.
Published 2015

Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death

by Del Nagro, Christopher J, Choi, Jonathan, Xiao, Yang, Rangell, Linda, Mohan, Sankar, Pandita, Ajay, Zha, Jiping, Jackson, Peter K, O’Brien, Thomas
Published 2014

Evaluation of assay interference and interpretation of CXCR4 receptor occupancy results in a preclinical study with MEDI3185, a fully human antibody to CXCR4

by Schwickart, Martin, Chavez, Carlos, Henderson, Simon, Vainshtein, Inna, Standifer, Nathan, DelNagro, Christopher, Mehrzai, Freshta, Schneider, Amy, Roskos, Lorin, Liang, Meina
Published 2015