The malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape

by Modelska, A, Turro, E, Russell, R, Beaton, J, Sbarrato, T, Spriggs, K, Miller, J, Gräf, S, Provenzano, E, Blows, F, Pharoah, P, Caldas, C, Le Quesne, J
Published 2015

Resistance to HSP90 inhibition involving loss of MCL1 addiction

by Busacca, S, Law, E W P, Powley, I R, Proia, D A, Sequeira, M, Le Quesne, J, Klabatsa, A, Edwards, J M, Matchett, K B, Luo, J L, Pringle, J H, El-Tanani, M, MacFarlane, M, Fennell, D A
Published 2016

Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

by Halliday, M, Radford, H, Sekine, Y, Moreno, J, Verity, N, le Quesne, J, Ortori, C A, Barrett, D A, Fromont, C, Fischer, P M, Harding, H P, Ron, D, Mallucci, G R
Published 2015