TGF-β-Elicited Induction of Tissue Inhibitor of Metalloproteinases (TIMP)-3 Expression in Fibroblasts Involves Complex Interplay between Smad3, p38α, and ERK1/2

by Leivonen, Suvi-Katri, Lazaridis, Konstantinos, Decock, Julie, Chantry, Andrew, Edwards, Dylan R., Kähäri, Veli-Matti
Published 2013

Standardization of the experimental autoimmune myasthenia gravis (EAMG) model by immunization of rats with Torpedo californica acetylcholine receptors — Recommendations for methods...

by Losen, Mario, Martinez-Martinez, Pilar, Molenaar, Peter C., Lazaridis, Konstantinos, Tzartos, Socrates, Brenner, Talma, Duan, Rui-Sheng, Luo, Jie, Lindstrom, Jon, Kusner, Linda
Published 2015

Association between variants in inflammation and cancer-associated genes and risk and survival of cholangiocarcinoma

by Chaiteerakij, Roongruedee, Juran, Brian D, Aboelsoud, Mohammed M, Harmsen, William S, Moser, Catherine D, Giama, Nasra H, Allotey, Loretta K, Mettler, Teresa A, Baichoo, Esha, Zhang, Xiaodan, Therneau, Terry M, Lazaridis, Konstantinos N, Roberts, Lewis R
Published 2015

International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

by Cordell, Heather J., Han, Younghun, Mells, George F., Li, Yafang, Hirschfield, Gideon M., Greene, Casey S., Xie, Gang, Juran, Brian D., Zhu, Dakai, Qian, David C., Floyd, James A. B., Morley, Katherine I., Prati, Daniele, Lleo, Ana, Cusi, Daniele, Gershwin, M. Eric, Anderson, Carl A., Lazaridis, Konstantinos N., Invernizzi, Pietro, Seldin, Michael F., Sandford, Richard N., Amos, Christopher I., Siminovitch, Katherine A.
Published 2015

Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

by Ellinghaus, David, Jostins, Luke, Spain, Sarah L, Cortes, Adrian, Bethune, Jörn, Han, Buhm, Park, Yu Rang, Raychaudhuri, Soumya, Pouget, Jennie G, Hübenthal, Matthias, Folseraas, Trine, Wang, Yunpeng, Esko, Tonu, Metspalu, Andres, Westra, Harm-Jan, Franke, Lude, Pers, Tune H, Weersma, Rinse K, Collij, Valerie, D'Amato, Mauro, Halfvarson, Jonas, Jensen, Anders Boeck, Lieb, Wolfgang, Degenhardt, Franziska, Forstner, Andreas J, Hofmann, Andrea, Schreiber, Stefan, Mrowietz, Ulrich, Juran, Brian D, Lazaridis, Konstantinos N, Brunak, Søren, Dale, Anders M, Trembath, Richard C, Weidinger, Stephan, Weichenthal, Michael, Ellinghaus, Eva, Elder, James T, Barker, Jonathan NWN, Andreassen, Ole A, McGovern, Dermot P, Karlsen, Tom H, Barrett, Jeffrey C, Parkes, Miles, Brown, Matthew A, Franke, Andre
Published 2016

Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma

by Borad, Mitesh J., Champion, Mia D., Egan, Jan B., Liang, Winnie S., Fonseca, Rafael, Bryce, Alan H., McCullough, Ann E., Barrett, Michael T., Hunt, Katherine, Patel, Maitray D., Young, Scott W., Collins, Joseph M., Silva, Alvin C., Condjella, Rachel M., Block, Matthew, McWilliams, Robert R., Lazaridis, Konstantinos N., Klee, Eric W., Bible, Keith C., Harris, Pamela, Oliver, Gavin R., Bhavsar, Jaysheel D., Nair, Asha A., Middha, Sumit, Asmann, Yan, Kocher, Jean-Pierre, Schahl, Kimberly, Kipp, Benjamin R., Barr Fritcher, Emily G., Baker, Angela, Aldrich, Jessica, Kurdoglu, Ahmet, Izatt, Tyler, Christoforides, Alexis, Cherni, Irene, Nasser, Sara, Reiman, Rebecca, Phillips, Lori, McDonald, Jackie, Adkins, Jonathan, Mastrian, Stephen D., Placek, Pamela, Watanabe, Aprill T., LoBello, Janine, Han, Haiyong, Von Hoff, Daniel, Craig, David W., Stewart, A. Keith, Carpten, John D.
Published 2014

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

by Liu, Jimmy Z., Hov, Johannes Roksund, Folseraas, Trine, Ellinghaus, Eva, Rushbrook, Simon M., Doncheva, Nadezhda T., Andreassen, Ole A., Weersma, Rinse K., Weismüller, Tobias J., Eksteen, Bertus, Invernizzi, Pietro, Hirschfield, Gideon M., Gotthardt, Daniel Nils, Pares, Albert, Ellinghaus, David, Shah, Tejas, Juran, Brian D., Milkiewicz, Piotr, Rust, Christian, Schramm, Christoph, Müller, Tobias, Srivastava, Brijesh, Dalekos, Georgios, Nöthen, Markus M., Herms, Stefan, Winkelmann, Juliane, Mitrovic, Mitja, Braun, Felix, Ponsioen, Cyriel Y., Croucher, Peter J. P., Sterneck, Martina, Teufel, Andreas, Mason, Andrew L., Saarela, Janna, Leppa, Virpi, Dorfman, Ruslan, Alvaro, Domenico, Floreani, Annarosa, Onengut-Gumuscu, Suna, Rich, Stephen S., Thompson, Wesley K., Schork, Andrew J., Næss, Sigrid, Thomsen, Ingo, Mayr, Gabriele, König, Inke R., Hveem, Kristian, Cleynen, Isabelle, Gutierrez-Achury, Javier, Ricaño-Ponce, Isis, van Heel, David, Björnsson, Einar, Sandford, Richard N., Durie, Peter R., Melum, Espen, Vatn, Morten H, Silverberg, Mark S., Duerr, Richard H., Padyukov, Leonid, Brand, Stephan, Sans, Miquel, Annese, Vito, Achkar, Jean-Paul, Boberg, Kirsten Muri, Marschall, Hanns-Ulrich, Chazouillères, Olivier, Bowlus, Christopher L., Wijmenga, Cisca, Schrumpf, Erik, Vermeire, Severine, Albrecht, Mario, Rioux, John D., Alexander, Graeme, Bergquist, Annika, Cho, Judy, Schreiber, Stefan, Manns, Michael P., Färkkilä, Martti, Dale, Anders M., Chapman, Roger W., Lazaridis, Konstantinos N., Franke, Andre, Anderson, Carl A., Karlsen, Tom H.
Published 2013