When less is more: primary immunodeficiency with an autoinflammatory kick

by Giannelou, Angeliki, Zhou, Qing, Kastner, Daniel L.
Published 2014

Hypophosphatasia and the risk of atypical femur fractures: a case–control study

by Bhattacharyya, Timothy, Jha, Smita, Wang, Hongying, Kastner, Daniel L., Remmers, Elaine F.
Published 2016

Pyrin Inflammasome Activation and RhoA Signaling in the Autoinflammatory Diseases FMF and HIDS

by Park, Yong Hwan, Wood, Geryl, Kastner, Daniel L., Chae, Jae Jin
Published 2016

Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)

by Bulua, Ariel C., Simon, Anna, Maddipati, Ravikanth, Pelletier, Martin, Park, Heiyoung, Kim, Kye-Young, Sack, Michael N., Kastner, Daniel L., Siegel, Richard M.
Published 2011

PFAPA: a single phenotype with genetic heterogeneity

by Lapidus, Sivia K, Chitkara, Puja, Kim, Peter W, Aksentijevich, Ivona, Remmers, Elaine F, Feder, Henry, Barham, Beverly K, Jones, Anne, Ward, Michael M, Barron, Karyl S, Kastner, Daniel L, Stojanov, Silvia
Published 2012

Constitutively Activated NLRP3 Inflammasome Causes Inflammation and Abnormal Skeletal Development in Mice

by Bonar, Sheri L., Brydges, Susannah D., Mueller, James L., McGeough, Matthew D., Pena, Carla, Chen, Debbie, Grimston, Susan K., Hickman-Brecks, Cynthia L., Ravindran, Soumya, McAlinden, Audrey, Novack, Deborah V., Kastner, Daniel L., Civitelli, Roberto, Hoffman, Hal M., Mbalaviele, Gabriel
Published 2012

A Novel Unstable Duplication Upstream of HAS2 Predisposes to a Breed-Defining Skin Phenotype and a Periodic Fever Syndrome in Chinese Shar-Pei Dogs

by Olsson, Mia, Meadows, Jennifer R. S., Truvé, Katarina, Rosengren Pielberg, Gerli, Puppo, Francesca, Mauceli, Evan, Quilez, Javier, Tonomura, Noriko, Zanna, Giordana, Docampo, Maria José, Bassols, Anna, Avery, Anne C., Karlsson, Elinor K., Thomas, Anne, Kastner, Daniel L., Bongcam-Rudloff, Erik, Webster, Matthew T., Sanchez, Armand, Hedhammar, Åke, Remmers, Elaine F., Andersson, Leif, Ferrer, Lluis, Tintle, Linda, Lindblad-Toh, Kerstin
Published 2011

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

by Kirino, Yohei, Bertsias, George, Ishigatsubo, Yoshiaki, Mizuki, Nobuhisa, Tugal-Tutkun, Ilknur, Seyahi, Emire, Ozyazgan, Yilmaz, Sacli, F. Sevgi, Erer, Burak, Inoko, Hidetoshi, Emrence, Zeliha, Cakar, Atilla, Abaci, Neslihan, Ustek, Duran, Satorius, Colleen, Ueda, Atsuhisa, Takeno, Mitsuhiro, Kim, Yoonhee, Wood, Geryl M., Ombrello, Michael J., Meguro, Akira, Gül, Ahmet, Remmers, Elaine F., Kastner, Daniel L.
Published 2013

Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1β

by Kim, Man Lyang, Chae, Jae Jin, Park, Yong Hwan, De Nardo, Dominic, Stirzaker, Roslynn A., Ko, Hyun-Ja, Tye, Hazel, Cengia, Louise, DiRago, Ladina, Metcalf, Donald, Roberts, Andrew W., Kastner, Daniel L., Lew, Andrew M., Lyras, Dena, Kile, Benjamin T., Croker, Ben A., Masters, Seth L.
Published 2015

Control of the innate immune response by the mevalonate pathway

by Akula, Murali K., Shi, Man, Jiang, Zhaozhao, Foster, Celia E., Miao, David, Li, Annie S., Zhang, Xiaoman, Gavin, Ruth M., Forde, Sorcha D., Germain, Gail, Carpenter, Susan, Rosadini, Charles V., Gritsman, Kira, Chae, Jae Jin, Hampton, Randolph, Silverman, Neal, Gravallese, Ellen M., Kagan, Jonathan C., Fitzgerald, Katherine A., Kastner, Daniel L., Golenbock, Douglas T., Bergo, Martin O., Wang, Donghai
Published 2016

Systemic juvenile idiopathic arthritis is associated with HLA-DRB1 in Europeans and Americans of European descent

by Ombrello, Michael, Remmers, Elaine F, Grom, Alexei A, Thomson, Wendy, Martini, Alberto, Gattorno, Marco, Ozen, Seza, Gul, Ahmet, Bohnsack, John F, Zeft, Andrew S, Mellins, Elizabeth D, Park, Jane L, Len, Claudio, Satorius, Colleen, Russo, Ricardo AG, Finkel, Terri H, Yeung, Rae SM, Schneider, Rayfel, Prahalad, Sampath, Glass, David N, Allen, Roger C, Wulffraat, Nico, Quartier, Pierre, Hilario, Maria Odete E, Murray, Kevin, Oliveira, Sheila, Anton, Jordi, Hinks, Anne, Zeggini, Eleftheria, Langefeld, Carl, Thompson, Susan, Chaitow, Jeffrey, Ellis, Justine, Singh, Davinder, Cavalvanti, Andre, Bica, Blanca, Sztajnbok, Flavio, Hakonarson, Hakon, Siminovitch, Katherine A, Minden, Kirsten, Haas, Peter, Schwarz, Tobias, Kastner, Daniel L, Woo, Patricia
Published 2012

Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early onset autoinflammatory syndrome

by Zhou, Qing, Wang, Hongying, Schwartz, Daniella M., Stoffels, Monique, Park, Yong Hwan, Zhang, Yuan, Yang, Dan, Demirkaya, Erkan, Takeuchi, Masaki, Tsai, Wanxia Li, Lyons, Jonathan J., Yu, Xiaomin, Ouyang, Claudia, Chen, Celeste, Chin, David T., Zaal, Kristien, Chandrasekharappa, Settara C., Hanson, Eric P., Yu, Zhen, Mullikin, James C., Hasni, Sarfaraz A., Wertz, Ingrid, Ombrello, Amanda K., Stone, Deborah L., Hoffmann, Patrycja, Jones, Anne, Barham, Beverly K., Leavis, Helen L., van Royen-Kerkof, Annet, Sibley, Cailin, Batu, Ezgi D., Gül, Ahmet, Siegel, Richard M., Boehm, Manfred, Milner, Joshua D., Ozen, Seza, Gadina, Massimo, Chae, JaeJin, Laxer, Ronald M., Kastner, Daniel L., Aksentijevich, Ivona
Published 2015

Genetic variants at CD28, PRDM1, and CD2/CD58 are associated with rheumatoid arthritis risk

by Raychaudhuri, Soumya, Thomson, Brian P., Remmers, Elaine F., Eyre, Stephen, Hinks, Anne, Guiducci, Candace, Catanese, Joseph J., Xie, Gang, Stahl, Eli A., Chen, Robert, Alfredsson, Lars, Amos, Christopher I., Ardlie, Kristin G., Barton, Anne, Bowes, John, Burtt, Noel P., Chang, Monica, Coblyn, Jonathan, Costenbader, Karen H., Criswell, Lindsey A., Crusius, J. Bart A., Cui, Jing, De Jager, Phillip L., Ding, Bo, Emery, Paul, Flynn, Edward, Harrison, Pille, Hocking, Lynne J., Huizinga, Tom W. J., Kastner, Daniel L., Ke, Xiayi, Kurreeman, Fina A. S., Lee, Annette T., Liu, Xiangdong, Li, Yonghong, Martin, Paul, Morgan, Ann W., Padyukov, Leonid, Reid, David M., Seielstad, Mark, Seldin, Michael F., Shadick, Nancy A., Steer, Sophia, Tak, Paul P., Thomson, Wendy, van der Helm-van Mil, Annette H. M., van der Horst-Bruinsma, Irene E., Weinblatt, Michael E., Wilson, Anthony G., Wolbink, Gert Jan, Wordsworth, Paul, Altshuler, David, Karlson, Elizabeth W., Toes, Rene E. M., de Vries, Niek, Begovich, Ann B., Siminovitch, Katherine A., Worthington, Jane, Klareskog, Lars, Gregersen, Peter K., Daly, Mark J., Plenge, Robert M.
Published 2009