The Role of Heat Shock Response in Insulin Resistance and Diabetes

by Kondo, Tatsuya, Motoshima, Hiroyuki, Igata, Motoyuki, Kawashima, Junji, Matsumura, Takeshi, Kai, Hirofumi, Araki, Eiichi
Published 2014

Mild Electrical Stimulation and Heat Shock Ameliorates Progressive Proteinuria and Renal Inflammation in Mouse Model of Alport Syndrome

by Koga, Tomoaki, Kai, Yukari, Fukuda, Ryosuke, Morino-Koga, Saori, Suico, Mary Ann, Koyama, Kosuke, Sato, Takashi, Shuto, Tsuyoshi, Kai, Hirofumi
Published 2012

Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter

by Suzuki, Shingo, Shuto, Tsuyoshi, Sato, Takashi, Kaneko, Masayuki, Takada, Tappei, Suico, Mary Ann, Cyr, Douglas M., Suzuki, Hiroshi, Kai, Hirofumi
Published 2014

Hyperthermia With Mild Electrical Stimulation Protects Pancreatic β-Cells From Cell Stresses and Apoptosis

by Kondo, Tatsuya, Sasaki, Kazunari, Matsuyama, Rina, Morino-Koga, Saori, Adachi, Hironori, Suico, Mary Ann, Kawashima, Junji, Motoshima, Hiroyuki, Furukawa, Noboru, Kai, Hirofumi, Araki, Eiichi
Published 2012

Inhibition of PDE4B suppresses inflammation by increasing expression of the deubiquitinase CYLD

by Komatsu, Kensei, Lee, Ji-Yun, Miyata, Masanori, Hyang Lim, Jae, Jono, Hirofumi, Koga, Tomoaki, Xu, Haidong, Yan, Chen, Kai, Hirofumi, Li, Jian-Dong
Published 2013

Diethyldithiocarbamate induces apoptosis in HHV-8-infected primary effusion lymphoma cells via inhibition of the NF-κB pathway

by MATSUNO, TAKASHI, KARIYA, RYUSHO, YANO, SHUICHIRO, MORINO-KOGA, SAORI, TAURA, MANABU, SUICO, MARY ANN, SHIMAUCHI, YUICHIRO, MATSUYAMA, SHINGO, OKAMOTO, YUKA, SHUTO, TSUYOSHI, KAI, HIROFUMI, OKADA, SEIJI
Published 2011

Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized, open-label, triple-arm trial

by Kondo, Tatsuya, Goto, Rieko, Ono, Kaoru, Kitano, Sayaka, Suico, Mary Ann, Sato, Miki, Igata, Motoyuki, Kawashima, Junji, Motoshima, Hiroyuki, Matsumura, Takeshi, Kai, Hirofumi, Araki, Eiichi
Published 2016

Mild Electrical Stimulation with Heat Shock Reduces Visceral Adiposity and Improves Metabolic Abnormalities in Subjects with Metabolic Syndrome or Type 2 Diabetes: Randomized Cross...

by Kondo, Tatsuya, Ono, Kaoru, Kitano, Sayaka, Matsuyama, Rina, Goto, Rieko, Suico, Mary Ann, Kawasaki, Shuji, Igata, Motoyuki, Kawashima, Junji, Motoshima, Hiroyuki, Matsumura, Takeshi, Kai, Hirofumi, Araki, Eiichi
Published 2014

Mild Electrical Stimulation Increases Stress Resistance and Suppresses Fat Accumulation via Activation of LKB1-AMPK Signaling Pathway in C. elegans

by Matsuyama, Shingo, Moriuchi, Masataka, Suico, Mary Ann, Yano, Shuichiro, Morino-Koga, Saori, Shuto, Tsuyoshi, Yamanaka, Kunitoshi, Kondo, Tatsuya, Araki, Eiichi, Kai, Hirofumi
Published 2014

Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M

by Miyata, Masanori, Lee, Ji-Yun, Susuki-Miyata, Seiko, Wang, Wenzhuo Y., Xu, Haidong, Kai, Hirofumi, Kobayashi, Koichi S., Flavell, Richard A., Li, Jian-Dong
Published 2015

Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases

by Shuto, Tsuyoshi, Kamei, Shunsuke, Nohara, Hirofumi, Fujikawa, Haruka, Tasaki, Yukihiro, Sugahara, Takuya, Ono, Tomomi, Matsumoto, Chizuru, Sakaguchi, Yuki, Maruta, Kasumi, Nakashima, Ryunosuke, Kawakami, Taisei, Suico, Mary Ann, Kondo, Yoshitaka, Ishigami, Akihito, Takeo, Toru, Tanaka, Ken-ichiro, Watanabe, Hiroshi, Nakagata, Naomi, Uchimura, Kohei, Kitamura, Kenichiro, Li, Jian-Dong, Kai, Hirofumi
Published 2016

TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs

by Suzuki, Shingo, Sargent, R Geoffrey, Illek, Beate, Fischer, Horst, Esmaeili-Shandiz, Alaleh, Yezzi, Michael J, Lee, Albert, Yang, Yanu, Kim, Soya, Renz, Peter, Qi, Zhongxia, Yu, Jingwei, Muench, Marcus O, Beyer, Ashley I, Guimarães, Alessander O, Ye, Lin, Chang, Judy, Fine, Eli J, Cradick, Thomas J, Bao, Gang, Rahdar, Meghdad, Porteus, Matthew H, Shuto, Tsuyoshi, Kai, Hirofumi, Kan, Yuet W, Gruenert, Dieter C
Published 2016