Proteasome inhibitors as experimental therapeutics of autoimmune diseases

by Verbrugge, Sue Ellen, Scheper, Rik J, Lems, Willem F, de Gruijl, Tanja D, Jansen, Gerrit
Published 2015

Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine

by Adema, Auke D, Floor, Karijn, Smid, Kees, Honeywell, Richard J, Scheffer, George L, Jansen, Gerrit, Peters, Godefridus J
Published 2014

High susceptibility of c-KIT+CD34+ precursors to prolonged doxorubicin exposure interferes with Langerhans cell differentiation in a human cell line model

by van de Ven, Rieneke, Verbrugge, Sue Ellen, Reurs, Anneke W., Bontkes, Hetty J., Hooijberg, Erik, Jansen, Gerrit, Scheper, Rik J., Scheffer, George L., de Gruijl, Tanja D.
Published 2011

Promising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis

by Gent, Yoony YJ, Weijers, Karin, Molthoff, Carla FM, Windhorst, Albert D, Huisman, Marc C, Kassiou, Michael, Jansen, Gerrit, Lammertsma, Adriaan A, van der Laken, Conny J
Published 2014

Effect of prednisone on type I interferon signature in rheumatoid arthritis: consequences for response prediction to rituximab

by de Jong, Tamarah D, Vosslamber, Saskia, Blits, Marjolein, Wolbink, Gertjan, Nurmohamed, Mike T, van der Laken, Conny J, Jansen, Gerrit, Voskuyl, Alexandre E, Verweij, Cornelis L
Published 2015

Sustained Macrophage Infiltration upon Multiple Intra-Articular Injections: An Improved Rat Model of Rheumatoid Arthritis for PET Guided Therapy Evaluation

by Chandrupatla, Durga M. S. H., Weijers, Karin, Gent, Yoony Y. J., de Greeuw, Inge, Lammertsma, Adriaan A., Jansen, Gerrit, van der Laken, Conny J., Molthoff, Carla F. M.
Published 2015

Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis

by Gent, Yoony YJ, Weijers, Karin, Molthoff, Carla FM, Windhorst, Albert D, Huisman, Marc C, Smith, Desirée EC, Kularatne, Sumith A, Jansen, Gerrit, Low, Philip S, Lammertsma, Adriaan A, van der Laken, Conny J
Published 2013

Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines

by Niewerth, Denise, Kaspers, Gertjan JL, Assaraf, Yehuda G, van Meerloo, Johan, Kirk, Christopher J, Anderl, Janet, Blank, Jonathan L, van de Ven, Peter M, Zweegman, Sonja, Jansen, Gerrit, Cloos, Jacqueline
Published 2014

Proteasome subunit expression analysis and chemosensitivity in relapsed paediatric acute leukaemia patients receiving bortezomib-containing chemotherapy

by Niewerth, Denise, Kaspers, Gertjan J. L., Jansen, Gerrit, van Meerloo, Johan, Zweegman, Sonja, Jenkins, Gaye, Whitlock, James A., Hunger, Stephen P., Lu, Xiaomin, Alonzo, Todd A., van de Ven, Peter M., Horton, Terzah M., Cloos, Jacqueline
Published 2016

Pharmacodynamic monitoring of (immuno)proteasome inhibition during bortezomib treatment of a critically ill patient with lupus nephritis and myocarditis

by de Groot, Karina A, Tsang a Sjoe, Michel, Niewerth, Denise, Cloos, Jacqueline, Blank, Jonathan L, Niessen, Hans W M, Zweegman, Sonja, Voskuyl, Alexandre E, Jansen, Gerrit, van der Heijden, Joost W
Published 2015

Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia

by Wojtuszkiewicz, Anna, Peters, Godefridus J., van Woerden, Nicole L., Dubbelman, Boas, Escherich, Gabriele, Schmiegelow, Kjeld, Sonneveld, Edwin, Pieters, Rob, van de Ven, Peter M., Jansen, Gerrit, Assaraf, Yehuda G., Kaspers, Gertjan J. L., Cloos, Jacqueline
Published 2015

Overcoming bortezomib resistance in human B cells by anti-CD20/rituximab-mediated complement-dependent cytotoxicity and epoxyketone-based irreversible proteasome inhibitors

by Verbrugge, Sue Ellen, Al, Marjon, Assaraf, Yehuda G, Niewerth, Denise, van Meerloo, Johan, Cloos, Jacqueline, van der Veer, Michael, Scheffer, George L, Peters, Godefridus J, Chan, Elena T, Anderl, Janet L, Kirk, Christopher J, Zweegman, Sonja, Dijkmans, Ben AC, Lems, Willem F, Scheper, Rik J, de Gruijl, Tanja D, Jansen, Gerrit
Published 2013

Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro...

by Verbrugge, Sue Ellen, Al, Marjon, Assaraf, Yehuda G., Kammerer, Sarah, Chandrupatla, Durga M.S.H., Honeywell, Richard, Musters, Rene P.J., Giovannetti, Elisa, O'Toole, Tom, Scheffer, George L., Krige, David, de Gruijl, Tanja D., Niessen, Hans W.M., Lems, Willem F., Kramer, Pieternella A., Scheper, Rik J., Cloos, Jacqueline, Ossenkoppele, Gert J., Peters, Godefridus J., Jansen, Gerrit
Published 2015