Genomic Analysis of wig-1 Pathways

by Sedaghat, Yalda, Mazur, Curt, Sabripour, Mahyar, Hung, Gene, Monia, Brett P.
Published 2012

Peripheral SMN restoration is essential for long-term rescue of a severe SMA mouse model

by Hua, Yimin, Sahashi, Kentaro, Rigo, Frank, Hung, Gene, Horev, Guy, Bennett, C. Frank, Krainer, Adrian R.
Published 2011

CD40 Generation 2.5 Antisense Oligonucleotide Treatment Attenuates Doxorubicin-induced Nephropathy and Kidney Inflammation

by Donner, Aaron J, Yeh, Steve T, Hung, Gene, Graham, Mark J, Crooke, Rosanne M, Mullick, Adam E
Published 2015

Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals

by Swayze, Eric E., Siwkowski, Andrew M., Wancewicz, Edward V., Migawa, Michael T., Wyrzykiewicz, Tadeusz K., Hung, Gene, Monia, Brett P., Bennett, and C. Frank
Published 2007

Intracerebral Infusion of Antisense Oligonucleotides Into Prion-infected Mice

by Nazor Friberg, Karah, Hung, Gene, Wancewicz, Ed, Giles, Kurt, Black, Chris, Freier, Sue, Bennett, Frank, DeArmond, Stephen J, Freyman, Yevgeniy, Lessard, Pierre, Ghaemmaghami, Sina, Prusiner, Stanley B
Published 2012

Viable RNaseH1 knockout mice show RNaseH1 is essential for R loop processing, mitochondrial and liver function

by Lima, Walt F., Murray, Heather M., Damle, Sagar S., Hart, Christopher E., Hung, Gene, De Hoyos, Cheryl Li, Liang, Xue-Hai, Crooke, Stanley T.
Published 2016

Pathological impact of SMN2 mis-splicing in adult SMA mice

by Sahashi, Kentaro, Ling, Karen K Y, Hua, Yimin, Wilkinson, John Erby, Nomakuchi, Tomoki, Rigo, Frank, Hung, Gene, Xu, David, Jiang, Ya-Ping, Lin, Richard Z, Ko, Chien-Ping, Bennett, C Frank, Krainer, Adrian R
Published 2013

Hepatotoxicity of high affinity gapmer antisense oligonucleotides is mediated by RNase H1 dependent promiscuous reduction of very long pre-mRNA transcripts

by Burel, Sebastien A., Hart, Christopher E., Cauntay, Patrick, Hsiao, Jill, Machemer, Todd, Katz, Melanie, Watt, Andy, Bui, Huynh-hoa, Younis, Husam, Sabripour, Mahyar, Freier, Susan M., Hung, Gene, Dan, Amy, Prakash, T.P., Seth, Punit P., Swayze, Eric E., Bennett, C. Frank, Crooke, Stanley T., Henry, Scott P.
Published 2016

Allele-Specific Suppression of Mutant Huntingtin Using Antisense Oligonucleotides: Providing a Therapeutic Option for All Huntington Disease Patients

by Skotte, Niels H., Southwell, Amber L., Østergaard, Michael E., Carroll, Jeffrey B., Warby, Simon C., Doty, Crystal N., Petoukhov, Eugenia, Vaid, Kuljeet, Kordasiewicz, Holly, Watt, Andrew T., Freier, Susan M., Hung, Gene, Seth, Punit P., Bennett, C. Frank, Swayze, Eric E., Hayden, Michael R.
Published 2014