Two-stage model-based design of cancer phase I dose escalation trials: evaluation using the phase I program of barasertib (AZD1152)

by Keizer, Ron J., Zandvliet, Anthe S., Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Published 2011

Proton Pump Inhibitor Prophylaxis After Gastric Bypass Does Not Cause Hypomagnesemia

by Boerlage, Thomas C. C., van Hees, Charlotte L. E., Huitema, Alwin D. R., Lauw, Fanny N.
Published 2016

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen

by de Vries Schultink, Aurelia H. M., Zwart, Wilbert, Linn, Sabine C., Beijnen, Jos H., Huitema, Alwin D. R.
Published 2015

Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses

by Keizer, Ron J, Jansen, Robert S, Rosing, Hilde, Thijssen, Bas, Beijnen, Jos H, Schellens, Jan H M, Huitema, Alwin D R
Published 2015

Pharmacokinetics of Selected Anticancer Drugs in Elderly Cancer Patients: Focus on Breast Cancer

by Crombag, Marie-Rose B.S., Joerger, Markus, Thürlimann, Beat, Schellens, Jan H.M., Beijnen, Jos H., Huitema, Alwin D.R.
Published 2016

Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy

by van Hasselt, J. G. Coen, Allegaert, Karel, van Calsteren, Kristel, Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Published 2014

A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients

by van Erp, Nielka P., van Herpen, Carla M., de Wit, Djoeke, Willemsen, Annelieke, Burger, David M., Huitema, Alwin D. R., Kapiteijn, Ellen, ter Heine, Rob
Published 2016

Corrigendum to “Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy”

by van Hasselt, J. G. Coen, Allegaert, Karel, van Calsteren, Kristel, Beijnen, Jos H., Schellens, Jan H. M., Huitema, Alwin D. R.
Published 2015

Predictive ability of a semi-mechanistic model for neutropenia in the development of novel anti-cancer agents: two case studies

by Soto, Elena, Keizer, Ron J., Trocóniz, Iñaki F., Huitema, Alwin D. R., Beijnen, Jos H., Schellens, Jan H. M., Wanders, Jantien, Cendrós, Josep María, Obach, Rosendo, Peraire, Concepción, Friberg, Lena E., Karlsson, Mats O.
Published 2010

Pharmacokinetics and excretion of 14C-omacetaxine in patients with advanced solid tumors

by Nijenhuis, Cynthia M., Hellriegel, Edward, Beijnen, Jos H., Hershock, Diane, Huitema, Alwin D. R., Lucas, Luc, Mergui-Roelvink, Marja, Munteanu, Mihaela, Rabinovich-Guilatt, Laura, Robertson, Philmore, Rosing, Hilde, Spiegelstein, Ofer, Schellens, Jan H. M.
Published 2016