Development of tools for quantitative intracellular metabolomics of Aspergillus niger chemostat cultures

by Lameiras, Francisca, Heijnen, Joseph J., van Gulik, Walter M.
Published 2015

A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kinetics

by Nikerel, I Emrah, van Winden, Wouter A, van Gulik, Walter M, Heijnen, Joseph J
Published 2006

Optimization of cold methanol quenching for quantitative metabolomics of Penicillium chrysogenum

by de Jonge, Lodewijk P., Douma, Rutger D., Heijnen, Joseph J., van Gulik, Walter M.
Published 2011

Substrate cycles in Penicillium chrysogenum quantified by isotopic non-stationary flux analysis

by Zhao, Zheng, ten Pierick, Angela, de Jonge, Lodewijk, Heijnen, Joseph J, Wahl, S Aljoscha
Published 2012

Fast “Feast/Famine” Cycles for Studying Microbial Physiology Under Dynamic Conditions: A Case Study with Saccharomyces cerevisiae

by Suarez-Mendez, Camilo A., Sousa, Andre, Heijnen, Joseph J., Wahl, Aljoscha
Published 2014

Quantitative metabolomics analysis of amino acid metabolism in recombinant Pichia pastoris under different oxygen availability conditions

by Carnicer, Marc, ten Pierick, Angela, van Dam, Jan, Heijnen, Joseph J, Albiol, Joan, van Gulik, Walter, Ferrer, Pau
Published 2012

Euler‐Lagrange computational fluid dynamics for (bio)reactor scale down: An analysis of organism lifelines

by Haringa, Cees, Tang, Wenjun, Deshmukh, Amit T., Xia, Jianye, Reuss, Matthias, Heijnen, Joseph J., Mudde, Robert F., Noorman, Henk J.
Published 2016

Development of quantitative metabolomics for Pichia pastoris

by Carnicer, Marc, Canelas, André B., ten Pierick, Angela, Zeng, Zhen, van Dam, Jan, Albiol, Joan, Ferrer, Pau, Heijnen, Joseph J., van Gulik, Walter
Published 2011

Effect of iclR and arcA knockouts on biomass formation and metabolic fluxes in Escherichia coli K12 and its implications on understanding the metabolism of Escherichia coli BL21 (D...

by Waegeman, Hendrik, Beauprez, Joeri, Moens, Helena, Maertens, Jo, De Mey, Marjan, Foulquié-Moreno, Maria R, Heijnen, Joseph J, Charlier, Daniel, Soetaert, Wim
Published 2011

Similar temperature dependencies of glycolytic enzymes: an evolutionary adaptation to temperature dynamics?

by Cruz, Ana Luisa B, Hebly, Marit, Duong, Giang-Huong, Wahl, Sebastian A, Pronk, Jack T, Heijnen, Joseph J, Daran-Lapujade, Pascale, van Gulik, Walter M
Published 2012

Glucose-methanol co-utilization in Pichia pastoris studied by metabolomics and instationary 13C flux analysis

by Jordà, Joel, Suarez, Camilo, Carnicer, Marc, ten Pierick, Angela, Heijnen, Joseph J, van Gulik, Walter, Ferrer, Pau, Albiol, Joan, Wahl, Aljoscha
Published 2013

Determination of the Cytosolic NADPH/NADP Ratio in Saccharomyces cerevisiae using Shikimate Dehydrogenase as Sensor Reaction

by Zhang, Jinrui, Pierick, Angela ten, van Rossum, Harmen M., Maleki Seifar, Reza, Ras, Cor, Daran, Jean-Marc, Heijnen, Joseph J., Aljoscha Wahl, S.
Published 2015

Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach

by Douma, Rutger D, Batista, Joana M, Touw, Kai M, Kiel, Jan AKW, Krikken, Arjen M, Zhao, Zheng, Veiga, Tânia, Klaassen, Paul, Bovenberg, Roel AL, Daran, Jean-Marc, Heijnen, Joseph J, van Gulik, Walter M
Published 2011