Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization

by Han, Kunkun, Xu, Xin, Chen, Guodong, Zeng, Yuanying, Zhu, Jingyu, Du, Xiaolin, Zhang, Zubin, Cao, Biyin, Liu, Zhaopeng, Mao, Xinliang
Published 2014

SC06, a novel small molecule compound, displays preclinical activity against multiple myeloma by disrupting the mTOR signaling pathway

by Han, Kunkun, Xu, Xin, Xu, Zhuan, Chen, Guodong, Zeng, Yuanying, Zhang, Zubin, Cao, Biyin, Kong, Yan, Tang, Xiaowen, Mao, Xinliang
Published 2015

Clioquinol induces pro-death autophagy in leukemia and myeloma cells by disrupting the mTOR signaling pathway

by Cao, Biyin, Li, Jie, Zhou, Xiumin, Juan, Jiaxiang, Han, Kunkun, Zhang, Zubin, Kong, Yan, Wang, Jianrong, Mao, Xinliang
Published 2014

A novel PI3K inhibitor PIK-C98 displays potent preclinical activity against multiple myeloma

by Zhu, Jingyu, Wang, Man, Yu, Yang, Qi, Huixin, Han, Kunkun, Tang, Juan, Zhang, Zubin, Zeng, Yuanying, Cao, Biyin, Qiao, Chunhua, Zhang, Hongjian, Hou, Tingjun, Mao, Xinliang
Published 2014

A novel small molecule agent displays potent anti-myeloma activity by inhibiting the JAK2-STAT3 signaling pathway

by Zhang, Zubin, Mao, Hongwu, Du, Xiaolin, Zhu, Jingyu, Xu, Yujia, Wang, Siyu, Xu, Xin, Ji, Peng, Yu, Yang, Cao, Biyin, Han, Kunkun, Hou, Tingjun, Xu, Zhuan, Kong, Yan, Jiang, Gaofeng, Tang, Xiaowen, Qiao, Chunhua, Mao, Xinliang
Published 2016