The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin

by Giles, Ian, Lambrianides, Nancy, Latchman, David, Chen, Pojen, Chukwuocha, Reginald, Isenberg, David, Rahman, Anisur
Published 2005

Antibodies to domain I of β-2-glycoprotein I and IgA antiphospholipid antibodies in patients with ‘seronegative’ antiphospholipid syndrome

by Cousins, Laura, Pericleous, Charis, Khamashta, Munther, Bertolaccini, Maria Laura, Ioannou, Yiannis, Giles, Ian, Rahman, Anisur
Published 2015

A novel expression system of domain I of human beta2 glycoprotein I in Escherichia coli

by Ioannou, Yiannis, Giles, Ian, Lambrianides, Anastasia, Richardson, Chris, Pearl, Laurence H, Latchman, David S, Isenberg, David A, Rahman, Anisur
Published 2006

The BILAG2004-Pregnancy index is reliable for assessment of disease activity in pregnant SLE patients

by Yee, Chee-Seng, Akil, Mohammed, Khamashta, Munther, Bessant, Rupa, Kilding, Rachael, Giles, Ian, Farewell, Vernon T., Gordon, Caroline
Published 2012

Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study

by Croca, Sara, Bassett, Paul, Pericleous, Charis, Alber, Karim Fouad, Latchman, David, Isenberg, David, Giles, Ian, Rahman, Anisur, Ioannou, Yiannis
Published 2014

Purified IgG from Patients with Obstetric but not IgG from Non-obstetric Antiphospholipid Syndrome Inhibit Trophoblast Invasion

by Poulton, Katie, Ripoll, Vera M, Pericleous, Charis, Meroni, Pier Luigi, Gerosa, Maria, Ioannou, Yiannis, Rahman, Anisur, Giles, Ian P
Published 2015

Development of a high yield expression and purification system for Domain I of Beta-2-glycoprotein I for the treatment of APS

by McDonnell, Thomas, Pericleous, Charis, Laurine, Emmanuelle, Tommasi, Rita, Garza-Garcia, Acely, Giles, Ian, Ioannou, Yiannis, Rahman, Anisur
Published 2015

Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays

by Artim-Esen, Bahar, Pericleous, Charis, Mackie, Ian, Ripoll, Vera M, Latchman, David, Isenberg, David, Rahman, Anisur, Ioannou, Yiannis, Giles, Ian
Published 2015

Evaluating the conformation of recombinant domain I of β2-glycoprotein I and its interaction with human monoclonal antibodies

by Pericleous, Charis, Miles, Jennifer, Esposito, Diego, Garza-Garcia, Acely, Driscoll, Paul C., Lambrianides, Anastasia, Latchman, David, Isenberg, David, Rahman, Anisur, Ioannou, Yiannis, Giles, Ian
Published 2011

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study

by Croca, Sara, Bassett, Paul, Chambers, Sharon, Davari, Maria, Alber, Karim Fouad, Leach, Oliver, Ioannou, Yiannis, Giles, Ian, Isenberg, David, Rahman, Anisur
Published 2015

Interactions of human monoclonal and polyclonal antiphospholipid antibodies with serine proteases involved in hemostasis

by Lambrianides, Anastasia, Turner-Stokes, Tabitha, Pericleous, Charis, Ehsanullah, Jasmine, Papadimitraki, Eva, Poulton, Katie, Ioannou, Yiannis, Lawrie, Andrew, Mackie, Ian, Chen, Pojen, Latchman, David, Isenberg, David, Rahman, Anisur, Giles, Ian
Published 2011

Measuring IgA Anti-β2-Glycoprotein I and IgG/IgA Anti-Domain I Antibodies Adds Value to Current Serological Assays for the Antiphospholipid Syndrome

by Pericleous, Charis, Ferreira, Isabel, Borghi, Orietta, Pregnolato, Francesca, McDonnell, Thomas, Garza-Garcia, Acely, Driscoll, Paul, Pierangeli, Silvia, Isenberg, David, Ioannou, Yiannis, Giles, Ian, Meroni, Pier Luigi, Rahman, Anisur
Published 2016

Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β2-glycoprotein I in a mouse model of anti-phospholipid antibody-...

by Pericleous, Charis, Ruiz-Limón, Patricia, Romay-Penabad, Zurina, Marín, Ana Carrera, Garza-Garcia, Acely, Murfitt, Lucy, Driscoll, Paul C., Latchman, David S., Isenberg, David A., Giles, Ian, Ioannou, Yiannis, Rahman, Anisur, Pierangeli, Silvia S.
Published 2015

Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjögren's syndrome

by Newton, Julia L, Frith, James, Powell, Danielle, Hackett, Kate, Wilton, Katharine, Bowman, Simon, Price, Elizabeth, Pease, Colin, Andrews, Jacqueline, Emery, Paul, Hunter, John, Gupta, Monica, Vadivelu, Saravanan, Giles, Ian, Isenberg, David, Lanyon, Peter, Jones, Adrian, Regan, Marian, Cooper, Annie, Moots, Robert, Sutcliffe, Nurhan, Bombardieri, Michele, Pitzalis, Costantino, McLaren, John, Young-Min, Steven, Dasgupta, Bhaskar, Griffiths, Bridget, Lendrem, Dennis, Mitchell, Sheryl, Ng, Wan-Fai
Published 2012

Fatigue in primary Sjögren's syndrome is associated with lower levels of proinflammatory cytokines

by Howard Tripp, Nadia, Tarn, Jessica, Natasari, Andini, Gillespie, Colin, Mitchell, Sheryl, Hackett, Katie L, Bowman, Simon J, Price, Elizabeth, Pease, Colin T, Emery, Paul, Lanyon, Peter, Hunter, John, Gupta, Monica, Bombardieri, Michele, Sutcliffe, Nurhan, Pitzalis, Costantino, McLaren, John, Cooper, Annie, Regan, Marian, Giles, Ian, Isenberg, David A, Saravanan, Vadivelu, Coady, David, Dasgupta, Bhaskar, McHugh, Neil, Young-Min, Steven, Moots, Robert, Gendi, Nagui, Akil, Mohammed, Griffiths, Bridget, Lendrem, Dennis W, Ng, Wan-Fai
Published 2016

A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren’s Syndrome

by James, Katherine, Al-Ali, Shereen, Tarn, Jessica, Cockell, Simon J., Gillespie, Colin S., Hindmarsh, Victoria, Locke, James, Mitchell, Sheryl, Lendrem, Dennis, Bowman, Simon, Price, Elizabeth, Pease, Colin T., Emery, Paul, Lanyon, Peter, Hunter, John A., Gupta, Monica, Bombardieri, Michele, Sutcliffe, Nurhan, Pitzalis, Costantino, McLaren, John, Cooper, Annie, Regan, Marian, Giles, Ian, Isenberg, David, Saravanan, Vadivelu, Coady, David, Dasgupta, Bhaskar, McHugh, Neil, Young-Min, Steven, Moots, Robert, Gendi, Nagui, Akil, Mohammed, Griffiths, Bridget, Wipat, Anil, Newton, Julia, Jones, David E., Isaacs, John, Hallinan, Jennifer, Ng, Wan-Fai
Published 2015