Precision oncology for patients with advanced cancer: the challenges of malignant snowflakes

by Kurzrock, Razelle, Giles, Francis J
Published 2015

Targeting autophagy: a novel anticancer strategy with therapeutic implications for imatinib resistance

by Carew, Jennifer S, Nawrocki, Steffan T, Giles, Francis J, Cleveland, John L
Published 2008

Evolving Therapeutic Strategies for the Classic Philadelphia-Negative Myeloproliferative Neoplasms

by Kaplan, Jason B., Stein, Brady L., McMahon, Brandon, Giles, Francis J., Platanias, Leonidas C.
Published 2016

The novel Aurora A kinase inhibitor MLN8237 is active in resistant chronic myeloid leukaemia and significantly increases the efficacy of nilotinib

by Kelly, Kevin R, Ecsedy, Jeffrey, Medina, Ernest, Mahalingam, Devalingam, Padmanabhan, Swaminathan, Nawrocki, Steffan T, Giles, Francis J, Carew, Jennifer S
Published 2011

ELR510444 Inhibits Tumor Growth and Angiogenesis by Abrogating HIF Activity and Disrupting Microtubules in Renal Cell Carcinoma

by Carew, Jennifer S., Esquivel, Juan A., Espitia, Claudia M., Schultes, Christoph M., Mülbaier, Marcel, Lewis, Joe D., Janssen, Bernd, Giles, Francis J., Nawrocki, Steffan T.
Published 2012

Preclinical Testing of Erlotinib in a Transgenic Alveolar Rhabdomyosarcoma Mouse Model

by Abraham, Jinu, Nelon, Laura D., Kubicek, Courtney B., Kilcoyne, Aoife, Hampton, Sheila T., Zarzabal, Lee Ann, Giles, Francis J., Michalek, Joel E., Rubin, Brian P., Keller, Charles
Published 2011

Targeting of glioblastoma cell lines and glioma stem cells by combined PIM kinase and PI3K-p110α inhibition

by Iqbal, Asneha, Eckerdt, Frank, Bell, Jonathan, Nakano, Ichiro, Giles, Francis J., Cheng, Shi-Yuan, Lulla, Rishi R., Goldman, Stewart, Platanias, Leonidas C.
Published 2016

Genomic landscape of DNA repair genes in cancer

by Chae, Young Kwang, Anker, Jonathan F., Carneiro, Benedito A., Chandra, Sunandana, Kaplan, Jason, Kalyan, Aparna, Santa-Maria, Cesar A., Platanias, Leonidas C., Giles, Francis J.
Published 2016

FGFR3–TACC3: A novel gene fusion in cervical cancer

by Carneiro, Benedito A., Elvin, Julia A., Kamath, Suneel D., Ali, Siraj M., Paintal, Ajit S., Restrepo, Alvaro, Berry, Emily, Giles, Francis J., Johnson, Melissa L.
Published 2015

Spotlight on lenvatinib in the treatment of thyroid cancer: patient selection and perspectives

by Costa, Ricardo, Carneiro, Benedito A, Chandra, Sunandana, Pai, Sachin G, Chae, Young Kwang, Kaplan, Jason B, Garrett, Hannah B, Agulnik, Mark, Kopp, Peter A, Giles, Francis J
Published 2016

Nilotinib in patients with systemic mastocytosis: analysis of the phase 2, open-label, single-arm nilotinib registration study

by Hochhaus, Andreas, Baccarani, Michele, Giles, Francis J., le Coutre, Philipp D., Müller, Martin C., Reiter, Andreas, Santanastasio, Helene, Leung, Mimi, Novick, Steven, Kantarjian, Hagop M.
Published 2015

Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase

by Colamonici, Marco, Blyth, Gavin, Saleiro, Diana, Szilard, Amy, Bliss-Moreau, Meghan, Giles, Francis J., Altman, Jessica K., Beauchamp, Elspeth M., Platanias, Leonidas C.
Published 2015

Pre-clinical evidence of PIM kinase inhibitor activity in BCR-ABL1 unmutated and mutated Philadelphia chromosome-positive (Ph+) leukemias

by Curi, Dany A., Beauchamp, Elspeth M., Blyth, Gavin T., Arslan, Ahmet Dirim, Donato, Nicholas J., Giles, Francis J., Altman, Jessica K., Platanias, Leonidas C.
Published 2015

Adenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profiling

by Chae, Young Kwang, Chung, Su Yun, Davis, Andrew A., Carneiro, Benedito A., Chandra, Sunandana, Kaplan, Jason, Kalyan, Aparna, Giles, Francis J.
Published 2015