Evolutionary conservation of codon optimality reveals hidden signatures of co-translational folding

by Pechmann, Sebastian, Frydman, Judith
Published 2012

Interplay between Chaperones and Protein Disorder Promotes the Evolution of Protein Networks

by Pechmann, Sebastian, Frydman, Judith
Published 2014

Hsp90 Inhibitors Exhibit Resistance-Free Antiviral Activity against Respiratory Syncytial Virus

by Geller, Ron, Andino, Raul, Frydman, Judith
Published 2013

The Dynamic Conformational Cycle of the Group I Chaperonin C-Termini Revealed via Molecular Dynamics Simulation

by Dalton, Kevin M., Frydman, Judith, Pande, Vijay S.
Published 2015

Cotranslational signal independent SRP preloading during membrane targeting

by Chartron, Justin W., Hunt, Katherine C. L., Frydman, Judith
Published 2016

Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness to stress

by Escusa-Toret, Stéphanie, Vonk, Willianne I. M., Frydman, Judith
Published 2013

Defining the Specificity of Cotranslationally Acting Chaperones by Systematic Analysis of mRNAs Associated with Ribosome-Nascent Chain Complexes

by del Alamo, Marta, Hogan, Daniel J., Pechmann, Sebastian, Albanese, Veronique, Brown, Patrick O., Frydman, Judith
Published 2011

Heterozygous Yeast Deletion Collection Screens Reveal Essential Targets of Hsp90

by Franzosa, Eric A., Albanèse, Véronique, Frydman, Judith, Xia, Yu, McClellan, Amie J.
Published 2011

The Interaction of the Chaperonin Tailless Complex Polypeptide 1 (Tcp1) Ring Complex (Tric) with Ribosome-Bound Nascent Chains Examined Using Photo-Cross-Linking

by McCallum, Christine D., Do, Hung, Johnson, Arthur E., Frydman, Judith
Published 2000

Super-resolution fluorescence imaging of intracellular mutant huntingtin protein reveals a population of fibrillar aggregates co-existing with compact perinuclear inclusion bodies

by Sahl, Steffen J, Weiss, Lucien E, Lau, Lana, Frydman, Judith, Moerner, WE
Published 2013

Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species

by Sahl, Steffen J., Weiss, Lucien E., Duim, Whitney C., Frydman, Judith, Moerner, W. E.
Published 2012

Super-Resolution Fluorescence of Huntingtin Reveals Growth of Globular Species into Short Fibers and Coexistence of Distinct Aggregates

by Duim, Whitney C., Jiang, Yan, Shen, Koning, Frydman, Judith, Moerner, W. E.
Published 2014

Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin

by Kasembeli, Moses, Lau, Wilson Chun Yu, Roh, Soung-Hun, Eckols, T. Kris, Frydman, Judith, Chiu, Wah, Tweardy, David J.
Published 2014

Delayed emergence of subdiffractionsized mutant huntingtin fibrils following inclusion body formation

by Sahl, Steffen J., Lau, Lana, Vonk, Willianne I. M., Weiss, Lucien E., Frydman, Judith, Moerner, W. E.
Published 2015

Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle

by Cong, Yao, Schröder, Gunnar F, Meyer, Anne S, Jakana, Joanita, Ma, Boxue, Dougherty, Matthew T, Schmid, Michael F, Reissmann, Stefanie, Levitt, Michael, Ludtke, Steven L, Frydman, Judith, Chiu, Wah
Published 2012

TRiC’s tricks inhibit huntingtin aggregation

by Shahmoradian, Sarah H, Galaz-Montoya, Jesus G, Schmid, Michael F, Cong, Yao, Ma, Boxue, Spiess, Christoph, Frydman, Judith, Ludtke, Steven J, Chiu, Wah
Published 2013

Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction

by Hanebuth, Marie A., Kityk, Roman, Fries, Sandra J., Jain, Alok, Kriel, Allison, Albanese, Veronique, Frickey, Tancred, Peter, Christine, Mayer, Matthias P., Frydman, Judith, Deuerling, Elke
Published 2016

Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract

by Shen, Koning, Calamini, Barbara, Fauerbach, Jonathan A, Ma, Boxue, Shahmoradian, Sarah H, Serrano Lachapel, Ivana L, Chiu, Wah, Lo, Donald C, Frydman, Judith
Published 2016