A nanobody modulates the p53 transcriptional program without perturbing its functional architecture

by Bethuyne, Jonas, De Gieter, Steven, Zwaenepoel, Olivier, Garcia-Pino, Abel, Durinck, Kaat, Verhelle, Adriaan, Hassanzadeh-Ghassabeh, Gholamreza, Speleman, Frank, Loris, Remy, Gettemans, Jan
Published 2014

Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia

by Kalender Atak, Zeynep, Gianfelici, Valentina, Hulselmans, Gert, De Keersmaecker, Kim, Devasia, Arun George, Geerdens, Ellen, Mentens, Nicole, Chiaretti, Sabina, Durinck, Kaat, Uyttebroeck, Anne, Vandenberghe, Peter, Wlodarska, Iwona, Cloos, Jacqueline, Foà, Robin, Speleman, Frank, Cools, Jan, Aerts, Stein
Published 2013

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

by Van de Walle, Inge, Dolens, Anne-Catherine, Durinck, Kaat, De Mulder, Katrien, Van Loocke, Wouter, Damle, Sagar, Waegemans, Els, De Medts, Jelle, Velghe, Imke, De Smedt, Magda, Vandekerckhove, Bart, Kerre, Tessa, Plum, Jean, Leclercq, Georges, Rothenberg, Ellen V., Van Vlierberghe, Pieter, Speleman, Frank, Taghon, Tom
Published 2016

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling

by Goossens, Steven, Radaelli, Enrico, Blanchet, Odile, Durinck, Kaat, Van der Meulen, Joni, Peirs, Sofie, Taghon, Tom, Tremblay, Cedric S., Costa, Magdaline, Ghahremani, Morvarid Farhang, De Medts, Jelle, Bartunkova, Sonia, Haigh, Katharina, Schwab, Claire, Farla, Natalie, Pieters, Tim, Matthijssens, Filip, Van Roy, Nadine, Best, J. Adam, Deswarte, Kim, Bogaert, Pieter, Carmichael, Catherine, Rickard, Adam, Suryani, Santi, Bracken, Lauryn S., Alserihi, Raed, Canté-Barrett, Kirsten, Haenebalcke, Lieven, Clappier, Emmanuelle, Rondou, Pieter, Slowicka, Karolina, Huylebroeck, Danny, Goldrath, Ananda W., Janzen, Viktor, McCormack, Matthew P., Lock, Richard B., Curtis, David J., Harrison, Christine, Berx, Geert, Speleman, Frank, Meijerink, Jules P. P., Soulier, Jean, Van Vlierberghe, Pieter, Haigh, Jody J.
Published 2015