Immunological features of α-synuclein in Parkinson's disease

by Roodveldt, Cintia, Christodoulou, John, Dobson, Christopher M
Published 2008

A Simple Lattice Model That Captures Protein Folding, Aggregation and Amyloid Formation

by Abeln, Sanne, Vendruscolo, Michele, Dobson, Christopher M., Frenkel, Daan
Published 2014

Structural Reorganisation and Potential Toxicity of Oligomeric Species Formed during the Assembly of Amyloid Fibrils

by Cheon, Mookyung, Chang, Iksoo, Mohanty, Sandipan, Luheshi, Leila M, Dobson, Christopher M, Vendruscolo, Michele, Favrin, Giorgio
Published 2007

The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila

by Gregory, Jenna M., Barros, Teresa P., Meehan, Sarah, Dobson, Christopher M., Luheshi, Leila M.
Published 2012

Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments

by Cohen, Samuel I. A., Vendruscolo, Michele, Dobson, Christopher M., Knowles, Tuomas P. J.
Published 2011

Inversion of the Balance between Hydrophobic and Hydrogen Bonding Interactions in Protein Folding and Aggregation

by Fitzpatrick, Anthony W., Knowles, Tuomas P. J., Waudby, Christopher A., Vendruscolo, Michele, Dobson, Christopher M.
Published 2011

Direct Observation of the Three Regions in α-Synuclein that Determine its Membrane-Bound Behaviour

by Fusco, Giuliana, De Simone, Alfonso, Tata, Gopinath, Vostrikov, Vitaly, Vendruscolo, Michele, Dobson, Christopher M., Veglia, Gianluigi
Published 2014

Direct Observation of Heterogeneous Amyloid Fibril Growth Kinetics via Two-Color Super-Resolution Microscopy

by Pinotsi, Dorothea, Buell, Alexander K., Galvagnion, Celine, Dobson, Christopher M., Kaminski Schierle, Gabriele S., Kaminski, Clemens F.
Published 2013

A Label-Free, Quantitative Assay of Amyloid Fibril Growth Based on Intrinsic Fluorescence

by Pinotsi, Dorothea, Buell, Alexander K, Dobson, Christopher M, Kaminski Schierle, Gabriele S, Kaminski, Clemens F
Published 2013

Bifunctional Anti-Non-Amyloid Component α-Synuclein Nanobodies Are Protective In Situ

by Butler, David C., Joshi, Shubhada N., Genst, Erwin De, Baghel, Ankit S., Dobson, Christopher M., Messer, Anne
Published 2016

A protein homeostasis signature in healthy brains recapitulates tissue vulnerability to Alzheimer’s disease

by Freer, Rosie, Sormanni, Pietro, Vecchi, Giulia, Ciryam, Prajwal, Dobson, Christopher M., Vendruscolo, Michele
Published 2016

Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity

by Fusco, Giuliana, De Simone, Alfonso, Arosio, Paolo, Vendruscolo, Michele, Veglia, Gianluigi, Dobson, Christopher M.
Published 2016

Solvent exposure of Tyr10 as a probe of structural differences between monomeric and aggregated forms of the amyloid-β peptide

by Aran Terol, Pablo, Kumita, Janet R., Hook, Sharon C., Dobson, Christopher M., Esbjörner, Elin K.
Published 2015

Alpha-2-Macroglobulin Is Acutely Sensitive to Freezing and Lyophilization: Implications for Structural and Functional Studies

by Wyatt, Amy R., Kumita, Janet R., Farrawell, Natalie E., Dobson, Christopher M., Wilson, Mark R.
Published 2015

A Relationship between the Transient Structure in the Monomeric State and the Aggregation Propensities of α-Synuclein and β-Synuclein

by Allison, Jane R., Rivers, Robert C., Christodoulou, John C., Vendruscolo, Michele, Dobson, Christopher M.
Published 2014

Structure of a low-population intermediate state in the release of an enzyme product

by De Simone, Alfonso, Aprile, Francesco A, Dhulesia, Anne, Dobson, Christopher M, Vendruscolo, Michele
Published 2015

Native-state stability determines the extent of degradation relative to secretion of protein variants from Pichia pastoris

by Whyteside, Graham, Alcocer, Marcos J.C., Kumita, Janet R., Dobson, Christopher M., Lazarou, Maria, Pleass, Richard J., Archer, David B.
Published 2011

Native-State Stability Determines the Extent of Degradation Relative to Secretion of Protein Variants from Pichia pastoris

by Whyteside, Graham, Alcocer, Marcos J. C., Kumita, Janet R., Dobson, Christopher M., Lazarou, Maria, Pleass, Richard J., Archer, David B.
Published 2011

In-Cell NMR Characterization of the Secondary Structure Populations of a Disordered Conformation of α-Synuclein within E. coli Cells

by Waudby, Christopher A., Camilloni, Carlo, Fitzpatrick, Anthony W. P., Cabrita, Lisa D., Dobson, Christopher M., Vendruscolo, Michele, Christodoulou, John
Published 2013

Analysis of the Native Structure, Stability and Aggregation of Biotinylated Human Lysozyme

by Ahn, Minkoo, De Genst, Erwin, Kaminski Schierle, Gabriele S., Erdelyi, Miklos, Kaminski, Clemens F., Dobson, Christopher M., Kumita, Janet R.
Published 2012