Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma

by Vormoor, Britta, Curtin, Nicola J.
Published 2014

Visualization of a DNA-PK/PARP1 complex

by Spagnolo, Laura, Barbeau, Jody, Curtin, Nicola J., Morris, Edward P., Pearl, Laurence H.
Published 2012

Targeting the DNA Double Strand Break Repair Machinery in Prostate Cancer

by Shaheen, Fadhel S., Znojek, Pawel, Fisher, Ann, Webster, Martin, Plummer, Ruth, Gaughan, Luke, Smith, Graeme C. M., Leung, Hing Y., Curtin, Nicola J., Robson, Craig N.
Published 2011

Clinicopathological features of homologous recombination deficient epithelial ovarian cancers: sensitivity to PARP inhibitors, platinum and survival

by Mukhophadyay, Asima, Plummer, Elizabeth R, Elattar, Ahmed, San, SooHoo, Uzir, Bisha Fathamah, Quinn, Jennifer E, Edmondson, Richard J, Curtin, Nicola J, Harriet, Aneke, Maxwell, Perry, McCluggage, W Glenn
Published 2012

The Use of Ovarian Cancer Cells from Patients Undergoing Surgery to Generate Primary Cultures Capable of Undergoing Functional Analysis

by O′Donnell, Rachel L., McCormick, Aiste, Mukhopadhyay, Asima, Woodhouse, Laura C., Moat, Madeleine, Grundy, Anna, Dixon, Michelle, Kaufman, Angelika, Soohoo, San, Elattar, Ahmed, Curtin, Nicola J., Edmondson, Richard J.
Published 2014

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition

by Middleton, Fiona K., Patterson, Miranda J., Elstob, Claire J., Fordham, Sarah, Herriott, Ashleigh, Wade, Mark A., McCormick, Aiste, Edmondson, Richard, May, Felicity E.B., Allan, James M., Pollard, John R., Curtin, Nicola J.
Published 2015

High‐resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers

by Dent, Barry M., Ogle, Laura F., O'Donnell, Rachel L., Hayes, Nicholas, Malik, Ujjal, Curtin, Nicola J., Boddy, Alan V., Plummer, E. Ruth, Edmondson, Richard J., Reeves, Helen L., May, Felicity E.B., Jamieson, David
Published 2015

PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia

by Herriott, Ashleigh, Tudhope, Susan J., Junge, Gesa, Rodrigues, Natalie, Patterson, Miranda J., Woodhouse, Laura, Lunec, John, Hunter, Jill E., Mulligan, Evan A., Cole, Michael, Allinson, Lisa M., Wallis, Jonathan P., Marshall, Scott, Wang, Evelyn, Curtin, Nicola J., Willmore, Elaine
Published 2015

COMPROMISED CDK1 ACTIVITY SENSITIZES BRCA-PROFICIENT CANCERS TO PARP INHIBITION

by Johnson, Neil, Li, Yu-Chen, Walton, Zandra E., Cheng, Katherine A., Li, Danan, Rodig, Scott J., Moreau, Lisa A., Unitt, Christine, Bronson, Roderick T., Thomas, Huw D., Newell, David R., D’Andrea, Alan D., Curtin, Nicola J., Wong, Kwok-Kin, Shapiro, Geoffrey I.
Published 2011

Vasoactivity of Rucaparib, a PARP-1 Inhibitor, is a Complex Process that Involves Myosin Light Chain Kinase, P2 Receptors, and PARP Itself

by McCrudden, Cian M., O’Rourke, Martin G., Cherry, Kim E., Yuen, Hiu-Fung, O’Rourke, Declan, Babur, Muhammad, Telfer, Brian A., Thomas, Huw D., Keane, Patrick, Nambirajan, Thiagarajan, Hagan, Chris, O’Sullivan, Joe M., Shaw, Chris, Williams, Kaye J., Curtin, Nicola J., Hirst, David G., Robson, Tracy
Published 2015

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

by Eccles, Suzanne A, Aboagye, Eric O, Ali, Simak, Anderson, Annie S, Armes, Jo, Berditchevski, Fedor, Blaydes, Jeremy P, Brennan, Keith, Brown, Nicola J, Bryant, Helen E, Bundred, Nigel J, Burchell, Joy M, Campbell, Anna M, Carroll, Jason S, Clarke, Robert B, Coles, Charlotte E, Cook, Gary JR, Cox, Angela, Curtin, Nicola J, Dekker, Lodewijk V, dos Santos Silva, Isabel, Duffy, Stephen W, Easton, Douglas F, Eccles, Diana M, Edwards, Dylan R, Edwards, Joanne, Evans, D Gareth, Fenlon, Deborah F, Flanagan, James M, Foster, Claire, Gallagher, William M, Garcia-Closas, Montserrat, Gee, Julia M W, Gescher, Andy J, Goh, Vicky, Groves, Ashley M, Harvey, Amanda J, Harvie, Michelle, Hennessy, Bryan T, Hiscox, Stephen, Holen, Ingunn, Howell, Sacha J, Howell, Anthony, Hubbard, Gill, Hulbert-Williams, Nick, Hunter, Myra S, Jasani, Bharat, Jones, Louise J, Key, Timothy J, Kirwan, Cliona C, Kong, Anthony, Kunkler, Ian H, Langdon, Simon P, Leach, Martin O, Mann, David J, Marshall, John F, Martin, Lesley Ann, Martin, Stewart G, Macdougall, Jennifer E, Miles, David W, Miller, William R, Morris, Joanna R, Moss, Sue M, Mullan, Paul, Natrajan, Rachel, O’Connor, James PB, O’Connor, Rosemary, Palmieri, Carlo, Pharoah, Paul D P, Rakha, Emad A, Reed, Elizabeth, Robinson, Simon P, Sahai, Erik, Saxton, John M, Schmid, Peter, Smalley, Matthew J, Speirs, Valerie, Stein, Robert, Stingl, John, Streuli, Charles H, Tutt, Andrew N J, Velikova, Galina, Walker, Rosemary A, Watson, Christine J, Williams, Kaye J, Young, Leonie S, Thompson, Alastair M
Published 2013