Discovery of Adamantyl Heterocyclic Ketones as Potent 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors

by Su, Xiangdong, Vicker, Nigel, Thomas, Mark P, Pradaux-Caggiano, Fabienne, Halem, Heather, Culler, Michael D, Potter, Barry V L
Published 2011

Adamantyl Ethanone Pyridyl Derivatives: Potent and Selective Inhibitors of Human 11β-Hydroxysteroid Dehydrogenase Type 1

by Su, Xiangdong, Pradaux-Caggiano, Fabienne, Vicker, Nigel, Thomas, Mark P, Halem, Heather, Culler, Michael D, Potter, Barry V L
Published 2011

Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitors

by Su, Xiangdong, Halem, Heather A., Thomas, Mark P., Moutrille, Cecile, Culler, Michael D., Vicker, Nigel, Potter, Barry V.L.
Published 2012

Ghrelin and Its Analogues, BIM-28131 and BIM-28125, Improve Body Weight and Regulate the Expression of MuRF-1 and MAFbx in a Rat Heart Failure Model

by Palus, Sandra, Schur, Robert, Akashi, Yoshihiro J., Bockmeyer, Barbara, Datta, Rakesh, Halem, Heather, Dong, Jesse, Culler, Michael D., Adams, Volker, Anker, Stefan D., Springer, Jochen
Published 2011

Chronic Treatment With a Melanocortin-4 Receptor Agonist Causes Weight Loss, Reduces Insulin Resistance, and Improves Cardiovascular Function in Diet-Induced Obese Rhesus Macaques

by Kievit, Paul, Halem, Heather, Marks, Daniel L., Dong, Jesse Z., Glavas, Maria M., Sinnayah, Puspha, Pranger, Lindsay, Cowley, Michael A., Grove, Kevin L., Culler, Michael D.
Published 2013

Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model

by Lenk, Karsten, Palus, Sandra, Schur, Robert, Datta, Rakesh, Dong, Jesse, Culler, Michael D., Anker, Stefan, Springer, Jochen, Schuler, Gerhard, Adams, Volker
Published 2012

In1-ghrelin, a splice variant of ghrelin gene, is associated with the evolution and aggressiveness of human neuroendocrine tumors: Evidence from clinical, cellular and molecular pa...

by Luque, Raul M., Sampedro-Nuñez, Miguel, Gahete, Manuel D., Ramos-Levi, Ana, Ibáñez-Costa, Alejandro, Rivero-Cortés, Esther, Serrano-Somavilla, Ana, Adrados, Magdalena, Culler, Michael D., Castaño, Justo P., Marazuela, Mónica
Published 2015

Presence of sst5TMD4, a truncated splice variant of the somatostatin receptor subtype 5, is associated to features of increased aggressiveness in pancreatic neuroendocrine tumors

by Sampedro-Núñez, Miguel, Luque, Raúl M., Ramos-Levi, Ana M., Gahete, Manuel D., Serrano-Somavilla, Ana, Villa-Osaba, Alicia, Adrados, Magdalena, Ibáñez-Costa, Alejandro, Martín-Pérez, Elena, Culler, Michael D., Marazuela, Mónica, Castaño, Justo P.
Published 2015

The Truncated Isoform of Somatostatin Receptor5 (sst5TMD4) Is Associated with Poorly Differentiated Thyroid Cancer

by Puig-Domingo, Manel, Luque, Raúl M., Reverter, Jordi L., López-Sánchez, Laura M., Gahete, Manuel D., Culler, Michael D., Díaz-Soto, Gonzalo, Lomeña, Francisco, Squarcia, Mattia, Mate, José Luis, Mora, Mireia, Fernández-Cruz, Laureano, Vidal, Oscar, Alastrué, Antonio, Balibrea, Jose, Halperin, Irene, Mauricio, Dídac, Castaño, Justo P.
Published 2014

In1-ghrelin splicing variant is overexpressed in pituitary adenomas and increases their aggressive features

by Ibáñez-Costa, Alejandro, Gahete, Manuel D., Rivero-Cortés, Esther, Rincón-Fernández, David, Nelson, Richard, Beltrán, Manuel, de la Riva, Andrés, Japón, Miguel A., Venegas-Moreno, Eva, Gálvez, Ma Ángeles, García-Arnés, Juan A., Soto-Moreno, Alfonso, Morgan, Jennifer, Tsomaia, Natia, Culler, Michael D., Dieguez, Carlos, Castaño, Justo P., Luque, Raúl M.
Published 2015